Don E. Farthing, Ph.D.

Affiliations: 
2008 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Pharmaceutical Chemistry, Analytical Chemistry
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H Thomas Karnes grad student 2008 VCU
 (Investigation of inosine and hypoxanthine as biomarkers of cardiac ischemia in plasma of non-traumatic chest pain patients and a rapid analytical system for assessment.)
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Publications

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Farthing DE, Farthing CA, Xi L. (2015) Inosine and hypoxanthine as novel biomarkers for cardiac ischemia: from bench to point-of-care. Experimental Biology and Medicine (Maywood, N.J.). 240: 821-31
Fowler AA, Syed AA, Knowlson S, et al. (2014) Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis. Journal of Translational Medicine. 12: 32
Farthing DE, Sica D, Hindle M, et al. (2011) A rapid and simple chemiluminescence method for screening levels of inosine and hypoxanthine in non-traumatic chest pain patients. Luminescence : the Journal of Biological and Chemical Luminescence. 26: 65-75
Farthing CA, Farthing DE, Koka S, et al. (2010) A simple and sensitive HPLC fluorescence method for determination of tadalafil in mouse plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 2891-5
Farthing C, Farthing D, Brophy DF, et al. (2008) High-Performance Liquid Chromatographic Determination of Cefepime and Cefazolin in Human Plasma and Dialysate Chromatographia. 67: 365-368
Farthing D, Gehr L, Karnes HT, et al. (2007) Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 12: 623-34
Farthing D, Sica D, Gehr T, et al. (2007) An HPLC method for determination of inosine and hypoxanthine in human plasma from healthy volunteers and patients presenting with potential acute cardiac ischemia. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 854: 158-64
Farthing D, Xi L, Gehr L, et al. (2006) High-performance liquid chromatography (HPLC) determination of inosine, a potential biomarker for initial cardiac ischaemia, using isolated mouse hearts. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 11: 449-59
Farthing D, Sica DA, Fakhry I, et al. (2005) Simple HPLC-UV method for determination of iohexol, iothalamate, p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis. Journal of Chromatography B. 826: 267-272
Farthing D, Larus T, Fakhry I, et al. (2004) Liquid chromatography method for determination of bivalirudin in human plasma and urine using automated ortho-phthalaldehyde derivatization and fluorescence detection. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 802: 355-9
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