Delaine K. Ceholski, Ph.D.
Affiliations: | 2012 | Biochemistry | University of Alberta, Edmonton, Alberta, Canada |
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Parents
Sign in to add mentorHoward S. Young | grad student | 2012 | University of Alberta | |
(Molecular insights into the disease-causing mechanisms of human phospholamban mutations.) |
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Publications
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Raad N, Bittihn P, Cacheux M, et al. (2021) Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Due to Phospholamban R14del Mutation. Circulation |
Gorski PA, Ceholski DK, Young HS. (2017) Structure-Function Relationship of the SERCA Pump and Its Regulation by Phospholamban and Sarcolipin. Advances in Experimental Medicine and Biology. 981: 77-119 |
Young HS, Ceholski DK, Trieber CA. (2015) Deception in simplicity: hereditary phospholamban mutations in dilated cardiomyopathy. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 93: 1-7 |
Abrol N, Smolin N, Armanious G, et al. (2014) Phospholamban C-terminal residues are critical determinants of the structure and function of the calcium ATPase regulatory complex. The Journal of Biological Chemistry. 289: 25855-66 |
Abrol N, Smolin N, Ceholski DK, et al. (2014) Phospholamban C-Terminal Truncations Including Heart Failure Mutation L39Stop Decrease Membrane Localization and Oligomerization and Alter the Structure of the PLB-Serca Complex Biophysical Journal. 106: 566a-567a |
Ceholski DK, Trieber CA, Holmes CF, et al. (2012) Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A. The Journal of Biological Chemistry. 287: 26596-605 |
Ceholski DK, Trieber CA, Young HS. (2012) Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy. The Journal of Biological Chemistry. 287: 16521-9 |
Glaves JP, Trieber CA, Ceholski DK, et al. (2011) Phosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pump. Journal of Molecular Biology. 405: 707-23 |
Glaves JP, Trieber CA, Ceholski DK, et al. (2011) Phosphorylation and Mutation Induce an Order-To-Disorder Transition in the Cytoplasmic Domain of Phospholamban Biophysical Journal. 100: 343a-344a |
Afara MR, Trieber CA, Ceholski DK, et al. (2008) Peptide inhibitors use two related mechanisms to alter the apparent calcium affinity of the sarcoplasmic reticulum calcium pump. Biochemistry. 47: 9522-30 |