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William N. Lipscomb, PhD

University of Minnesota, Harvard 
Theoretical chemistry, chemical structure
"William Lipscomb"

(1919 - 2011)
Lipscomb, William Nunn Part 1. Electron diffraction investigations of vanadium tetrachloride, dimethylketene dimer, tetrachloroethylene, and trichloroethylene. Part 2. The crystal structure of methylammonium chloride. Dissertation (Ph.D.), California Institute of Technology (1946).
The Nobel Prize in Chemistry 1976 was awarded to William Lipscomb "for his studies on the structure of boranes illuminating problems of chemical bonding".

Mean distance: 6.24
Cross-listing: Crystallography Tree


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Linus Carl Pauling grad student 1946 Caltech
 (Part 1, Electron diffraction investigations of vanadium tetrachloride, dimethylketene dimer, tetrachloroethylene, and trichloroethylene; Part 2, The crystal structure of methylammonium chloride)
Verner F. Schomaker grad student 1946 Caltech


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Roger A. Hegstrom grad student Harvard (Physics Tree)
Gil Shoham grad student Harvard
William Henry Eberhardt grad student 1945 Caltech
Christer E. Nordman grad student 1953 UMN
Oleg Jardetzky grad student 1956 UMN
Richard E. Dickerson grad student 1957 UMN
Robert A. Jacobson grad student 1959 UMN
C. William Kern grad student 1961 UMN
Russell N. Grimes grad student 1962 University of Minnesota, Harvard
Roald Hoffmann grad student 1962 Harvard
Lawrence L. Lohr grad student 1963 Harvard
Russel M. Pitzer grad student 1963 Harvard
J. Zanos Gougoutas grad student 1964 Harvard
John Henry Enemark grad student 1966 Harvard
Thomas A. Steitz grad student 1966 Harvard
William England Palke grad student 1967 Harvard
Donald H. Voet grad student 1967 Harvard
Herbert Beall grad student 1963-1968 Harvard
Eugene Switkes grad student 1970 Harvard
Irving R. Epstein grad student 1971 Harvard
Don C. Wiley grad student 1972 Harvard
David A. Dixon grad student 1976 Harvard
Evan R. Kantrowitz grad student 1976 Harvard
Irene M. Pepperberg grad student 1976 Harvard (Neurotree)
Stephen I. Scheiner grad student 1976 Harvard
Douglas C. Rees grad student 1980 Harvard
Kurt  L. Krause grad student 1980-1986 University of Minnesota, Harvard
David W. Christianson grad student 1987 Harvard
John F. Stanton grad student 1984-1988 Harvard
J. Eric Gouaux grad student 1989 Harvard
Peter R. David grad student 1984-1990 Harvard
Yuh Min Chook grad student 1994 Harvard
Florante A. Quiocho post-doc Harvard
Michael G. Rossmann post-doc 1956-1958 UMN
Martha L. Ludwig post-doc 1967 Harvard
Robert Bau post-doc 1968-1969 Harvard
Evan R. Kantrowitz post-doc 1976-1977 Harvard
Joseph Vincent Ortiz post-doc 1982 Harvard
David H. Magers post-doc 1988-1989 Harvard
Stephen K. Burley post-doc 1987-1990 Harvard (Physics Tree)
Raymond C. Stevens post-doc 1989-1991 Harvard


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Koji Nakanishi collaborator Harvard
John H Hall collaborator 1970-1976 Harvard
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Sträter N, Lipscomb WN. (2013) Leucyl Aminopeptidase (Animal) Handbook of Proteolytic Enzymes. 2: 1465-1470
Lipscomb WN, Kantrowitz ER. (2012) Structure and mechanisms of Escherichia coli aspartate transcarbamoylase. Accounts of Chemical Research. 45: 444-53
Li H, Min D, Shore SG, et al. (2007) Nature of "hydrogen bond" in the diborane-benzene complex: covalent, electrostatic, or dispersive? Inorganic Chemistry. 46: 3956-9
Kong Y, Ma J, Karplus M, et al. (2006) The allosteric mechanism of yeast chorismate mutase: a dynamic analysis. Journal of Molecular Biology. 356: 237-47
Tomlinson S, Zheng C, Hosmane NS, et al. (2005) Chemistry of C-trimethylsilyl-substituted heterocarboranes. 31. New insights into reaction pathways of carborane ligand systems: Synthetic, structural, spectroscopic, and electrochemical studies on sandwich and half-sandwich metallacarboranes of iron, cobalt, and nickel Organometallics. 24: 2177-2187
Guo H, Cui Q, Lipscomb WN, et al. (2003) Understanding the role of active-site residues in chorismate mutase catalysis from molecular-dynamics simulations. Angewandte Chemie (International Ed. in English). 42: 1508-11
Dadashev V, Gindulyte A, Lipscomb WN, et al. (2002) Proposed New Materials: Boron Fullerenes, Nanotubes, and Nanotori Acs Symposium Series. 827: 79-102
Guo H, Cui Q, Lipscomb WN, et al. (2001) Substrate conformational transitions in the active site of chorismate mutase: their role in the catalytic mechanism. Proceedings of the National Academy of Sciences of the United States of America. 98: 9032-7
Hosmane NS, Zhang H, Maguire JA, et al. (2001) New stanna- and plumba-carboranes: Synthetic and structural investigation Main Group Metal Chemistry. 24: 589-596
Krappmann S, Lipscomb WN, Braus GH. (2000) Coevolution of transcriptional and allosteric regulation at the chorismate metabolic branch point of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 97: 13585-90
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