Ryan Z. Turncliff, Ph.D.

Affiliations: 
2004 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacy, Pharmacology, Cell Biology
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Parents

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Kim L.R. Brouwer grad student 2004 UNC Chapel Hill
 (Expression and function of transport proteins and CYP3A in sandwich-cultured hepatocytes: Application to the hepatobiliary disposition of drugs and generated metabolites.)
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Publications

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Turncliff RZ, Hoffmaster KA, Kalvass JC, et al. (2006) Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 318: 881-9
Turncliff RZ, Tian X, Brouwer KL. (2006) Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes. Biochemical Pharmacology. 71: 1520-9
Hoffmaster KA, Turncliff RZ, LeCluyse EL, et al. (2004) P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide. Pharmaceutical Research. 21: 1294-302
Turncliff RZ, Meier PJ, Brouwer KL. (2004) Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 834-9
Zamek-Gliszczynski MJ, Xiong H, Patel NJ, et al. (2003) Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver. The Journal of Pharmacology and Experimental Therapeutics. 304: 801-9
Annaert PP, Turncliff RZ, Booth CL, et al. (2001) P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 29: 1277-83
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