Scott J. Brantley, Ph.D.
Affiliations: | 2013 | Pharmaceutical Sciences | University of North Carolina, Chapel Hill, Chapel Hill, NC |
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Parents
Sign in to add mentor| Kim L.R. Brouwer | grad student | 2013 | UNC Chapel Hill | |
| (Translational Methods for Quantitative Prediction of Metabolic Herbal Product-Drug Interactions: Case Study with Milk Thistle.) | ||||
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| Brantley SJ, Argikar AA, Lin YS, et al. (2014) Herb-drug interactions: challenges and opportunities for improved predictions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 301-17 |
| Brantley SJ, Graf TN, Oberlies NH, et al. (2013) A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1662-70 |
| Sy-Cordero AA, Graf TN, Runyon SP, et al. (2013) Enhanced bioactivity of silybin B methylation products. Bioorganic & Medicinal Chemistry. 21: 742-7 |
| Kim E, Sy-Cordero A, Graf TN, et al. (2011) Isolation and identification of intestinal CYP3A inhibitors from cranberry (Vaccinium macrocarpon) using human intestinal microsomes. Planta Medica. 77: 265-70 |
| Ngo N, Brantley SJ, Carrizosa DR, et al. (2010) The warfarin-cranberry juice interaction revisited: A systematic in vitro-in vivo evaluation. Journal of Experimental Pharmacology. 2010: 83-91 |
| Brantley SJ, Oberlies NH, Kroll DJ, et al. (2010) Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations. The Journal of Pharmacology and Experimental Therapeutics. 332: 1081-7 |