Peter M. Scarbrough, Ph.D.

Affiliations: 
2011 Free Radical and Radiation Biology University of Iowa, Iowa City, IA 
Area:
Molecular Biology
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"Peter Scarbrough"
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Douglas R. Spitz grad student 2011 University of Iowa
 (Inhibitors of glucose and hydroperoxide metabolism potentiate 17AAG-induced cancer cell killing via metabolic oxidative stress.)
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Publications

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King KE, Kane JB, Scarbrough P, et al. (2016) Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example. Biodemography and Social Biology. 62: 87-104
Scarbrough PM, Weber RP, Iversen ES, et al. (2015) A Cross-Cancer Genetic Association Analysis of the DNA repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast and Colorectal Cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology
Siamakpour-Reihani S, Owzar K, Jiang C, et al. (2015) Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 31: 386-95
Li L, Fath MA, Scarbrough PM, et al. (2015) Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer. Redox Biology. 4: 127-35
Kennedy KM, Scarbrough PM, Ribeiro A, et al. (2013) Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer. Plos One. 8: e75154
Tolun AA, Scarbrough PM, Zhang H, et al. (2012) Systemic oxidative stress, as measured by urinary allantoin and F(2)-isoprostanes, is not increased in Down syndrome. Annals of Epidemiology. 22: 892-4
Siamakpour-Reihani S, Scarbrough PM, Wang F, et al. (2012) Systemic markers of oxidative status and colorectal adenomatous polyps. Annals of Epidemiology. 22: 587-91
Il'yasova D, Scarbrough P, Spasojevic I. (2012) Urinary biomarkers of oxidative status. Clinica Chimica Acta; International Journal of Clinical Chemistry. 413: 1446-53
Scarbrough PM, Mapuskar KA, Mattson DM, et al. (2012) Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress. Free Radical Biology & Medicine. 52: 436-43
Orcutt KP, Parsons AD, Sibenaller ZA, et al. (2011) Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4. Cancer Research. 71: 3932-40
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