Andrew J. Olaharski, Ph.D.

Affiliations: 
2004 University of California, Riverside, Riverside, CA, United States 
Area:
Molecular Biology, Oncology, Genetics
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David Eastmond grad student 2004 UC Riverside
 (Characterization of numerical chromosomal aberrations during cervical carcinogenesis.)
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Publications

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Ness D, Ren Z, Gardai S, et al. (2013) Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis. Plos One. 8: e66164
Fitzgerald K, Bergeron M, Willits C, et al. (2013) Pharmacological inhibition of polo like kinase 2 (PLK2) does not cause chromosomal damage or result in the formation of micronuclei. Toxicology and Applied Pharmacology. 269: 1-7
Fielden MR, Adai A, Dunn RT, et al. (2011) Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 54-74
Olaharski AJ, Albertini S, Mueller L, et al. (2011) GADD45α induction in the GreenScreen HC indicator assay does not occur independently of cytotoxicity. Environmental and Molecular Mutagenesis. 52: 28-34
Olaharski AJ, Bitter H, Gonzaludo N, et al. (2010) Modeling bone marrow toxicity using kinase structural motifs and the inhibition profiles of small molecular kinase inhibitors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 266-75
Olaharski AJ, Gonzaludo N, Bitter H, et al. (2009) Identification of a kinase profile that predicts chromosome damage induced by small molecule kinase inhibitors. Plos Computational Biology. 5: e1000446
Olaharski AJ, Uppal H, Cooper M, et al. (2009) In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates. Toxicology Letters. 188: 98-103
Fielden MR, Nie A, McMillian M, et al. (2008) Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 103: 28-34
Olaharski AJ, Ji Z, Woo JY, et al. (2006) The histone deacetylase inhibitor trichostatin a has genotoxic effects in human lymphoblasts in vitro. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 341-7
Olaharski AJ, Sotelo R, Solorza-Luna G, et al. (2006) Tetraploidy and chromosomal instability are early events during cervical carcinogenesis. Carcinogenesis. 27: 337-43
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