James L. Manley, Ph. D.

Biological Sciences Columbia University, New York, NY 
mRNA processing
"James L. Manley"


Mean distance: 16.59 (cluster 11)
Cross-listing: Neurotree


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Geoffrey Louis Zubay research assistant 1970-1972 Columbia
Raymond F. Gesteland grad student 1972-1976 SUNY Stony Brook
 (Properties of in vivo and in vitro synthesized abnormal polypeptides encoded by the lacZ gene of E. coli)
Malcolm L. Gefter post-doc 1977-1980 MIT


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Xin-Yuan Fu grad student 1988 Columbia
Baohe Shen grad student 2000 Columbia (Neurotree)
Moonkyoung Um grad student 2000 Columbia (Neurotree)
Zheng Chen grad student 2003 Columbia (Neurotree)
Saba Valadkhan grad student 2003 Columbia (Neurotree)
Chanseok Shin grad student 2004 Columbia (Neurotree)
Shuzo Kaneko grad student 2007 Columbia (Neurotree)
Adelene Y. Tan grad student 2010 Columbia (Neurotree)
Dafne Campigli Di Giammartino grad student 2014 Columbia (Neurotree)
Kevin Ryan post-doc 1999-2003 Columbia
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Carbone M, Amelio I, Affar EB, et al. (2018) Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine. Cell Death and Differentiation
Fomin V, Richard P, Hoque M, et al. (2018) The gene, implicated in ALS/FTD, encodes a protein that functions in control of endothelin and glutamate signaling. Molecular and Cellular Biology
Yamazaki T, Liu L, Lazarev D, et al. (2018) TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency. Genes & Development
Yurko N, Liu X, Yamazaki T, et al. (2017) MPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD. Molecular Cell. 68: 913-925.e3
Sun Y, Zhang Y, Hamilton K, et al. (2017) Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proceedings of the National Academy of Sciences of the United States of America
Liu X, Hoque M, Larochelle M, et al. (2017) Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe. Genome Research
Ogami K, Richard P, Chen Y, et al. (2017) An Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression. Genes & Development
Richard P, Vethantham V, Manley JL. (2017) Roles of Sumoylation in mRNA Processing and Metabolism. Advances in Experimental Medicine and Biology. 963: 15-33
Tian B, Manley JL. (2016) Alternative polyadenylation of mRNA precursors. Nature Reviews. Molecular Cell Biology
Conlon EG, Lu L, Sharma A, et al. (2016) The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS patient brains. Elife. 5
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