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Rachelle Gaudet, Ph.D.

Affiliations: 
2002- Molecular and Cellular Biology Harvard University, Cambridge, MA, United States 
Area:
Structural biology of signaling and transport through biological membranes
Website:
https://projects.iq.harvard.edu/gaudetlab/home
Google:
"Rachelle Gaudet"
Bio:

http://www.fas.harvard.edu/~biophys/Rachelle_Gaudet.htm
http://proquest.umi.com/pqdlink?did=734466791&Fmt=7&clientId =79356&RQT=309&VName=PQD

Mean distance: 8.18 (cluster 21)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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Paul B. Sigler grad student 1993-1998 Yale
 (Structural analysis of phosducin and its phosphorylation-regulated interaction with transducin beta-gamma)
Don C. Wiley post-doc 1998-2002 Harvard

Children

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Erik Procko grad student 2008 Harvard
Shamayeeta Ray post-doc Harvard
Xiangshu Jin post-doc 2003-2006 Harvard
Polina V. Lishko post-doc 2005-2006 Harvard
Marcos M. Sotomayor post-doc 2008-2013 Harvard
Ute A Hellmich post-doc 2012-2014 Harvard

Collaborators

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Paul A. Garrity collaborator 2020- (Neurotree)
BETA: Related publications

Publications

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Velilla JA, Volpe MR, Kenney GE, et al. (2022) Structural basis of colibactin activation by the ClbP peptidase. Nature Chemical Biology
Thomas C, Aller SG, Beis K, et al. (2020) Structural and functional diversity calls for a new classification of ABC transporters. Febs Letters
Srikant S, Gaudet R, Murray AW. (2020) Selecting for Altered Substrate Specificity Reveals the Evolutionary Flexibility of ATP-Binding Cassette Transporters. Current Biology : Cb
Bozzi AT, McCabe AL, Barnett BC, et al. (2019) Transmembrane helix 6b links proton- and metal-release pathways and drives conformational change in an Nramp-family transition metal transporter. The Journal of Biological Chemistry
Bozzi AT, Bane LB, Zimanyi CM, et al. (2019) Unique structural features in an Nramp metal transporter impart substrate-specific proton cotransport and a kinetic bias to favor import. The Journal of General Physiology
Srikant S, Gaudet R. (2019) Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters. Nature Structural & Molecular Biology
Nicoludis JM, Green AG, Walujkar S, et al. (2019) Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis. Proceedings of the National Academy of Sciences of the United States of America
Bozzi AT, Zimanyi CM, Nicoludis JM, et al. (2019) Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter. Elife. 8
Gaudet R, Jiang Y. (2019) Decision letter: Structure-based characterization of novel TRPV5 inhibitors Elife
Finol-Urdaneta RK, McArthur JR, Goldschen-Ohm MP, et al. (2018) Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels. The Journal of General Physiology
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