Kian Kani, Ph.D.

Affiliations: 
2006 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology
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Parents

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Ralf Landgraf grad student 2006 UCLA
 (The contribution of ERBB3 conformations to receptor activation states.)
Parag Kumar Mallick post-doc 2006-2010 USC Keck School of Medicine
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Publications

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Garri C, Howell S, Tiemann K, et al. (2018) Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2). Oncotarget. 9: 27363-27379
Frieboes HB, Curtis LT, Wu M, et al. (2015) Simulation of the Protein-Shedding Kinetics of a Fully Vascularized Tumor. Cancer Informatics. 14: 163-75
Kani K, Malihi PD, Jiang Y, et al. (2013) Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype. The Prostate. 73: 306-15
Chambers MC, Maclean B, Burke R, et al. (2012) A cross-platform toolkit for mass spectrometry and proteomics. Nature Biotechnology. 30: 918-20
Zhang Q, Park E, Kani K, et al. (2012) Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 13237-42
Kani K, Faca VM, Hughes LD, et al. (2012) Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibition. Molecular Cancer Therapeutics. 11: 1071-81
Kani K, Sordella R, Mallick P. (2012) Investigation of acquired resistance to EGFR-targeted therapies in lung cancer using cDNA microarrays. Methods in Molecular Biology (Clifton, N.J.). 795: 233-53
Fang Q, Kani K, Faca VM, et al. (2011) Impact of protein stability, cellular localization, and abundance on proteomic detection of tumor-derived proteins in plasma. Plos One. 6: e23090
Vogelsang MS, Kani K, Katz JE, et al. (2011) Model-based discovery of circulating biomarkers. Methods in Molecular Biology (Clifton, N.J.). 728: 87-107
Zhang Q, Park E, Kani K, et al. (2011) Abstract C58: Heterotetramers of ERBB2 and ERBB3 generate qualitatively distinct signals from heterodimers and provide most of the neuregulin-induced phosphorylation of ERBB2 Cancer Research. 71
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