Michael D. Hoos, Ph.D.

Affiliations: 
2009 Stony Brook University, Stony Brook, NY, United States 
Area:
Neuroscience Biology, Biochemistry, Cell Biology
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William E. Van Nostrand grad student 2009 SUNY Stony Brook
 (Inhibition of amyloid beta-protein fibrillogenesis by myelin basic protein.)
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Publications

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Zhu X, Xu F, Hoos MD, et al. (2020) Reduced Levels of Cerebrospinal Fluid/Plasma Aβ40 as an Early Biomarker for Cerebral Amyloid Angiopathy in RTg-DI Rats. International Journal of Molecular Sciences. 21
Davis J, Xu F, Hatfield J, et al. (2018) A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy. The American Journal of Pathology
Xu F, Davis J, Hoos M, et al. (2017) Mutation of the Kunitz-type proteinase inhibitor domain in the amyloid β-protein precursor abolishes its anti-thrombotic properties in vivo. Thrombosis Research. 155: 58-64
Nostrand WEV, Xu F, Fu Z, et al. (2016) Cerebral Vascular Amyloid Seeds Drive Amyloid Ss-Protein Fibril Assembly With A Distinct Anti-Parallel Structure Alzheimers & Dementia. 12: 391
Hoos MD, Richardson BM, Foster MW, et al. (2013) Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase. Journal of Proteome Research. 12: 4462-77
Kotarba AE, Aucoin D, Hoos MD, et al. (2013) Fine mapping of the amyloid β-protein binding site on myelin basic protein. Biochemistry. 52: 2565-73
Ridnour LA, Dhanapal S, Hoos M, et al. (2012) Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1. Journal of Neurochemistry. 123: 736-49
Liao MC, Hoos MD, Aucoin D, et al. (2010) N-terminal domain of myelin basic protein inhibits amyloid beta-protein fibril assembly. The Journal of Biological Chemistry. 285: 35590-8
Hoos MD, Ahmed M, Smith SO, et al. (2009) Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro. Biochemistry. 48: 4720-7
Hoos MD, Ahmed M, Smith SO, et al. (2007) Inhibition of familial cerebral amyloid angiopathy mutant amyloid beta-protein fibril assembly by myelin basic protein. The Journal of Biological Chemistry. 282: 9952-61
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