Preethi Krishnan, Ph.D.

Affiliations: 
2000 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacy
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"Preethi Krishnan"
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Parents

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Kenneth Bastow grad student 2000 UNC Chapel Hill
 (Study of pyranonaphthoquinones and protoberberines as DNA topoisomerase II inhibitors.)
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Publications

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Krishnan P, Schnell G, Tripathi R, et al. (2015) Analysis of HCV Genotype 1b Resistance Variants in Japanese Patients Treated with Paritaprevir/Ritonavir and Ombitasvir. Antimicrobial Agents and Chemotherapy
Schnell G, Tripathi R, Beyer J, et al. (2015) Hepatitis C Virus Genotype 4 Resistance and Subtype Demographic Characterization of Patients Treated with Ombitasvir plus Paritaprevir/ritonavir. Antimicrobial Agents and Chemotherapy
Krishnan P, Tripathi R, Schnell G, et al. (2015) Resistance Analysis of Baseline and Treatment-Emergent Variants in the AVIATOR Study With Paritaprevir/r, Ombitasvir and Dasabuvir in HCV Genotype 1. Antimicrobial Agents and Chemotherapy
Kati W, Koev G, Irvin M, et al. (2015) In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrobial Agents and Chemotherapy. 59: 1505-11
Krishnan P, Beyer J, Mistry N, et al. (2015) In vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5A. Antimicrobial Agents and Chemotherapy. 59: 979-87
DeGoey DA, Randolph JT, Liu D, et al. (2014) Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5A. Journal of Medicinal Chemistry. 57: 2047-57
DeGoey DA, Betebenner DA, Grampovnik DJ, et al. (2013) Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A. Bioorganic & Medicinal Chemistry Letters. 23: 3627-30
Peters-Libeu C, Miller J, Rutenber E, et al. (2012) Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. Journal of Molecular Biology. 421: 587-600
Miller J, Arrasate M, Brooks E, et al. (2011) Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34
He Y, King MS, Kempf DJ, et al. (2008) Relative replication capacity and selective advantage profiles of protease inhibitor-resistant hepatitis C virus (HCV) NS3 protease mutants in the HCV genotype 1b replicon system. Antimicrobial Agents and Chemotherapy. 52: 1101-10
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