Anders Skov Kristensen, Ph.D.

Affiliations: 
Medicinal Chemistry University of Copenhagen, København, Denmark 
Area:
Glutamate receptors, SLC6 transporters
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"Anders Skov Kristensen"
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Publications

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Bay Y, Venskutonytė R, Frantsen SM, et al. (2023) Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The Febs Journal
Francotte P, Bay Y, Goffin E, et al. (2023) Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry. 264: 116036
Chałupnik P, Vialko A, Pickering DS, et al. (2022) Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype. International Journal of Molecular Sciences. 23
Ismail V, Zachariassen LG, Godwin A, et al. (2022) Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome. American Journal of Human Genetics
Perszyk RE, Kristensen AS, Lyuboslavsky P, et al. (2021) Three-dimensional missense tolerance ratio analysis. Genome Research
Stenum-Berg C, Musgaard M, Chavez-Abiega S, et al. (2019) Mutational analysis and modeling of negative allosteric modulator binding sites in AMPA receptors. Molecular Pharmacology
Munro L, Ladefoged LK, Padmanathan V, et al. (2019) Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage Clamp Fluorometry. Molecular Pharmacology
Kate Ladefoged L, Munro L, Kristensen AS, et al. (2019) Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A Receptors Biophysical Journal. 116: 479a
Ladefoged LK, Munro L, Pedersen AJ, et al. (2018) Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor. Molecular Pharmacology
Stenum-Berg C, Abiega SC, Thisted CL, et al. (2017) Identification and Characterization of the Binding Pocket for Negative Allosteric Modulators in AMPA Receptors Biophysical Journal. 112: 418a
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