Henk Timmerman

Affiliations: 
Pharmacochemistry Vrije Universiteit Amsterdam, Amsterdam, Netherlands 
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"Henk Timmerman"
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Wybe Th. Nauta grad student 1967 Free University of Amsterdam
 (2-alkyl-1-[ortho-alkyl-phenyl] cyclohexanols, synthesis, conformation and some pharmacological investigations)
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Publications

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Kooistra AJ, de Graaf C, Timmerman H. (2014) The receptor concept in 3D: from hypothesis and metaphor to GPCR-ligand structures. Neurochemical Research. 39: 1850-61
Timmerman H. (2013) Medicinal and Pharmaceutical Chemistry Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Timmerman H. (2011) Simple solution to the Chinese herbs 'problem': Reflect and apply the rules | Simpele oplossing voor 'probleem' Chinese kruiden: Denk na en pas de regels toe Pharmaceutisch Weekblad. 146: 47
Wijtmans M, Denonne F, Célanire S, et al. (2010) Histamine H3 receptor ligands with a 3-cyclobutoxy motif: A novel and versatile constraint of the classical 3-propoxy linker Medchemcomm. 1: 39-44
Timmerman H, van der Goot H. (2010) Histamine receptors and their ligands: Mechanisms and applications Encyclopedia of Neuroscience. 1149-1166
Timmerman H, de Souza NJ. (2009) Medicinal chemistry teaching and training: a continuous adaptation. Chemmedchem. 4: 1055-8
Célanire S, Wijtmans M, Christophe B, et al. (2009) Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists. Chemmedchem. 4: 1063-8
Wijtmans M, Celanire S, Snip E, et al. (2008) 4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists. Journal of Medicinal Chemistry. 51: 2944-53
Bakker RA, Jongejan A, Sansuk K, et al. (2008) Constitutively active mutants of the histamine H1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class A G protein-coupled receptors. Molecular Pharmacology. 73: 94-103
Allen BPC, Nederkoorn PHJ, Timmerman H, et al. (2008) Monocation-driven proton transfer relays within G protein-coupled receptors of the rhodopsin class and the GTP synthase mechanism Journal of Molecular Structure: Theochem. 859: 51-68
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