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Douwe D. Breimer

Affiliations: 
pharmacology Leiden University, Leiden, Netherlands 
Website:
http://www.leidenuniv.nl/professoren/show.php3-medewerker_id=468.htm
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"Douwe Breimer"
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Parents

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Jacques M. van Rossum grad student 1974 Radboud University Nijmegen
 (Pharmacokinetics of hypnotic drugs : studies on the pharmacokinetics and biopharmaceutics of barbiturates and chloral hydrate in man)

Children

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Nico P.E. Vermeulen grad student 1980 Leiden
Jan  H.M. Schellens grad student 1988 Leiden
Ron A.A. Mathôt grad student 1995 Leiden

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Publications

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de Leede LG, de Boer AG, Havermans JP, et al. (2013) Avoidance of "first-pass" elimination of rectally administered propranolol in relation to the site of absorption in rats. Pharmaceutical Research. 1: 164-8
de Leede LG, de Boer AG, Feijen CD, et al. (2013) Site specific rectal drug administration in man with an osmotic system: influence on "first-pass" elimination of lidocaine. Pharmaceutical Research. 1: 129-34
Teunissen MW, Brorens IO, De Langen HJ, et al. (2013) Correlation between in vivo antipyrine metabolite formation and theophylline metabolism in rats. Pharmaceutical Research. 3: 156-61
van der Sandt IC, Gaillard PJ, Voorwinden HH, et al. (2001) P-glycoprotein inhibition leads to enhanced disruptive effects by anti-microtubule cytostatics at the in vitro blood-brain barrier. Pharmaceutical Research. 18: 587-92
de Lange EC, de Boer AG, Breimer DD. (2000) Methodological issues in microdialysis sampling for pharmacokinetic studies. Advanced Drug Delivery Reviews. 45: 125-48
de Lange EC, de Boer BA, Breimer DD. (1999) Microdialysis for pharmacokinetic analysis of drug transport to the brain. Advanced Drug Delivery Reviews. 36: 211-227
Mulders TM, Bergman DJ, Poll-The BT, et al. (1997) Abnormal glutathione conjugation in patients with tyrosinaemia type I. Journal of Inherited Metabolic Disease. 20: 473-85
Grouls RJ, Meert TF, Korsten HH, et al. (1997) Epidural and intrathecal n-butyl-p-aminobenzoate solution in the rat. Comparison with bupivacaine. Anesthesiology. 86: 181-7
De Boer AG, Breimer DD. (1997) Hepatic first-pass effect and controlled drug delivery following rectal administration Advanced Drug Delivery Reviews. 28: 229-237
Mathot RA, Wenden EM, Soudijn W, et al. (1996) Partial agonism of the nonselective adenosine receptor agonist 8-butylaminoadenosine at the A1 receptor in vivo. The Journal of Pharmacology and Experimental Therapeutics. 279: 1439-46
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