Martine Joyce Smit

chemistry Vrije Universiteit Amsterdam, Amsterdam, Netherlands 
Medicinal Chemistry
"Martine Smit"
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Rob Leurs grad student 1995 VU Amsterdam
Henk Timmerman grad student 1995 VU Amsterdam
 (Dynamic regulation of the histamine H₁ and H₂ receptors)
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van den Bor J, Bergkamp ND, Anbuhl SM, et al. (2023) NanoB to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET. Cell Reports Methods. 3: 100422
Paradis JS, Feng X, Murat B, et al. (2022) Computationally designed GPCR quaternary structures bias signaling pathway activation. Nature Communications. 13: 6826
Kleist AB, Jenjak S, Sente A, et al. (2022) Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor. Science (New York, N.Y.). 377: 222-228
Song S, Liu B, Habibie H, et al. (2021) D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. Ebiomedicine. 68: 103412
Zarca A, Perez C, van den Bor J, et al. (2021) Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization. Cells. 10
Işbilir A, Möller J, Arimont M, et al. (2020) Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists. Proceedings of the National Academy of Sciences of the United States of America
Smit MJ, Schlecht-Louf G, Neves M, et al. (2020) The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Targeting. Annual Review of Pharmacology and Toxicology
Daly CA, Smit MJ, Plouffe B. (2020) The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development. Biochemical Society Transactions
Bebelman MP, Crudden C, Pegtel DM, et al. (2020) The Convergence of Extracellular Vesicle and GPCR Biology. Trends in Pharmacological Sciences
Soave M, Heukers R, Kellam B, et al. (2020) Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies. Cell Chemical Biology
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