Martine Joyce Smit

Affiliations: 
chemistry Vrije Universiteit Amsterdam, Amsterdam, Netherlands 
Area:
Medicinal Chemistry
Website:
http://www.chem.vu.nl/en/news-agenda/news-archive/2010/prof-dr-martine-smit-in-science-signaling.asp
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"Martine Smit"
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SNBCP

Parents

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Rob Leurs grad student 1995 VU Amsterdam
Henk Timmerman grad student 1995 VU Amsterdam
 (Dynamic regulation of the histamine H₁ and H₂ receptors)
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Publications

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Zarca A, Adlere I, Viciano CP, et al. (2024) Pharmacological characterization and radiolabeling of VUF15485, a high-affinity small-molecule agonist for the atypical chemokine receptor ACKR3. Molecular Pharmacology
Bebelman MP, Setiawan IM, Bergkamp ND, et al. (2023) Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging. Iscience. 26: 107412
van den Bor J, Bergkamp ND, Anbuhl SM, et al. (2023) NanoB to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET. Cell Reports Methods. 3: 100422
Paradis JS, Feng X, Murat B, et al. (2022) Computationally designed GPCR quaternary structures bias signaling pathway activation. Nature Communications. 13: 6826
Kleist AB, Jenjak S, Sente A, et al. (2022) Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor. Science (New York, N.Y.). 377: 222-228
Song S, Liu B, Habibie H, et al. (2021) D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. Ebiomedicine. 68: 103412
Zarca A, Perez C, van den Bor J, et al. (2021) Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization. Cells. 10
Işbilir A, Möller J, Arimont M, et al. (2020) Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists. Proceedings of the National Academy of Sciences of the United States of America
Smit MJ, Schlecht-Louf G, Neves M, et al. (2020) The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Targeting. Annual Review of Pharmacology and Toxicology
Daly CA, Smit MJ, Plouffe B. (2020) The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development. Biochemical Society Transactions
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