Johannes L. Bos

Physiological Chemistry Utrecht University, Utrecht, Netherlands 
Ras mutations in human tumors
"Johannes Bos"

Mean distance: 10.13


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Piet Borst grad student 1980 Amsterdam
 (Structural analysis of yeast mitochondrial DNA : the region of the 21S ribosomal RNA gene)


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Rene Medema grad student 1989-1993 Utrecht (Cell Biology Tree)
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Post JB, Hami N, Mertens AEE, et al. (2019) CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition. Oncotarget. 10: 1440-1457
Bruurs LJM, van der Net MC, Zwakenberg S, et al. (2018) A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization. Plos One. 13: e0207159
Bruurs LJM, van der Net MC, Zwakenberg S, et al. (2018) The phosphatase PTPL1 is required for PTEN-mediated regulation of apical membrane size. Molecular and Cellular Biology
Pannekoek WJ, Vliem MJ, Bos JL. (2018) Multiple Rap1 effectors control Epac1-mediated tightening of endothelial junctions. Small Gtpases. 0
Bos JL. (2017) From Ras to Rap and Back, a Journey of 35 Years. Cold Spring Harbor Perspectives in Medicine
Bruurs LJ, Zwakenberg S, van der Net MC, et al. (2017) A two-tiered mechanism enables localized Cdc42 signaling during enterocyte polarization. Molecular and Cellular Biology
Rehmann H, Bos JL. (2016) Ras Association-Domain Dimers Bring Proteins Together. Structure (London, England : 1993). 24: 2039-2040
Verissimo CS, Overmeer RM, Ponsioen B, et al. (2016) Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening. Elife. 5
Bruurs LJ, Donker L, Zwakenberg S, et al. (2015) ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. The Journal of Cell Biology. 210: 1055-63
Post A, Pannekoek WJ, Ponsioen B, et al. (2015) Rap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation. Molecular and Cellular Biology. 35: 2495-502
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