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John E. Hearst

Affiliations: 
Chemistry University of California, Berkeley, Berkeley, CA, United States 
Area:
psoralen chemistry, mechanism of DNA repair, and photosynthesis
Website:
http://chemistry.berkeley.edu/publications/journal/volume9/no2/hearst.php
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"John E. Hearst"
Bio:

http://resolver.caltech.edu/CaltechETD:etd-04072006-090550

Mean distance: 7.82
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Parents

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S. Jonathan Singer research assistant Yale
Jerome R. Vinograd grad student 1961 Caltech
 (Ultracentrifuge studies on deoxyribonucleic acid and tobacco mosaic virus. I. The effect of angular velocity on the sedimentation velocity behavior of DNA and TMV. II. The three component theory of sedimentation equilibrium in a density gradient and ...)
Walter H. Stockmayer post-doc 1961-1962 Dartmouth

Children

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Carl William Schmid grad student 1968-1971 UC Berkeley
Michael R. Botchan grad student 1972 UC Berkeley
Thomas R. Cech grad student 1975 UC Berkeley
Douglas C. Youvan grad student 1981 UC Berkeley
Jason D. Kahn grad student 1984-1990 UC Berkeley
H Peter Spielmann grad student 1991 UC Berkeley
Donald H. Burke grad student 1992 UC Berkeley
Daniel B. Kim-Shapiro grad student 1993 UC Berkeley
Dae Yoon Chi post-doc 1986-1988 UC Berkeley
Daniel E. Falvey post-doc 1989 UC Berkeley

Collaborators

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Blaine H.M. Mooers collaborator 1994-1997 Oregon State
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Publications

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SHI YB, LIPSON SE, CHI DY, et al. (2010) ChemInform Abstract: Applications of Psoralens as Probes of Nucleic Acid Structure and Function Cheminform. 22: no-no
Lai C, Cao H, Hearst JE, et al. (2008) Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation. Analytical Chemistry. 80: 8790-8
Cao H, Hearst JE, Corash L, et al. (2008) LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells. Analytical Chemistry. 80: 2932-8
Hearst JE, Vinograd J. (2006) A THREE-COMPONENT THEORY OF SEDIMENTATION EQUILIBRIUM IN A DENSITY GRADIENT. Proceedings of the National Academy of Sciences of the United States of America. 47: 999-1004
Saffran WA, Ahmed S, Bellevue S, et al. (2004) DNA repair defects channel interstrand DNA cross-links into alternate recombinational and error-prone repair pathways. The Journal of Biological Chemistry. 279: 36462-9
Eichman BF, Mooers BH, Alberti M, et al. (2001) The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions. Journal of Molecular Biology. 308: 15-26
Mu D, Bessho T, Nechev LV, et al. (2000) DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts. Molecular and Cellular Biology. 20: 2446-54
Alkorta I, Park C, Kong J, et al. (1999) Rhodobacter capsulatus DNA topoisomerase I purification and characterization. Archives of Biochemistry and Biophysics. 362: 123-30
HEARST JE, VINOGRAD J. (1998) The net hydration of deoxyribonucleic acid. Proceedings of the National Academy of Sciences of the United States of America. 47: 825-30
HEARST JE, VINOGRAD J. (1998) The net hydration of T-4 bacteriophage deoxyribonuecleic acid and the effect of hydration on buoyant behavior in a density gradient at equilibrium in the ultracentrifuge. Proceedings of the National Academy of Sciences of the United States of America. 47: 1005-14
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