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John E. Hearst

Affiliations: 
Chemistry University of California, Berkeley, Berkeley, CA 
Area:
psoralen chemistry, mechanism of DNA repair, and photosynthesis
Website:
http://chemistry.berkeley.edu/publications/journal/volume9/no2/hearst.php
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"John E. Hearst"
Bio:

http://resolver.caltech.edu/CaltechETD:etd-04072006-090550

Mean distance: 7.82
 
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Parents

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S. Jonathan Singer research assistant Yale
Jerome R. Vinograd grad student 1961 Caltech
 (Ultracentrifuge studies on deoxyribonucleic acid and tobacco mosaic virus. I. The effect of angular velocity on the sedimentation velocity behavior of DNA and TMV. II. The three component theory of sedimentation equilibrium in a density gradient and ...)
Walter H. Stockmayer post-doc 1961-1962 Dartmouth

Children

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Carl William Schmid grad student 1968-1971 UC Berkeley
Michael R. Botchan grad student 1972 UC Berkeley
Thomas R. Cech grad student 1975 UC Berkeley
Douglas C. Youvan grad student 1981 UC Berkeley
Jason D. Kahn grad student 1984-1990 UC Berkeley
Donald H. Burke grad student 1992 UC Berkeley
Daniel B. Kim-Shapiro grad student 1993 UC Berkeley
Daniel E. Falvey post-doc 1989 UC Berkeley

Collaborators

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Blaine H. Mooers collaborator 1994-1997 Oregon State
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Publications

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Kanathezhath B, Mizokami M, Stanislaus S, et al. (2011) Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes. Experimental Biology and Medicine (Maywood, N.J.). 236: 492-504
Lai C, Cao H, Hearst JE, et al. (2008) Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation. Analytical Chemistry. 80: 8790-8
Cao H, Hearst JE, Corash L, et al. (2008) LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells. Analytical Chemistry. 80: 2932-8
Kuypers FA, Watson G, Sage E, et al. (2005) Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia. Annals of the New York Academy of Sciences. 1054: 214-22
Brockstedt DG, Bahjat KS, Giedlin MA, et al. (2005) Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity. Nature Medicine. 11: 853-60
Saffran WA, Ahmed S, Bellevue S, et al. (2004) DNA repair defects channel interstrand DNA cross-links into alternate recombinational and error-prone repair pathways. The Journal of Biological Chemistry. 279: 36462-9
Roback JD, Hossain MS, Lezhava L, et al. (2003) Allogeneic T cells treated with amotosalen prevent lethal cytomegalovirus disease without producing graft-versus-host disease following bone marrow transplantation. Journal of Immunology (Baltimore, Md. : 1950). 171: 6023-31
Johnson BD, Taylor PA, Stankowski MC, et al. (2002) Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or establishment of mixed chimerism. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 8: 581-7
Greenberg RB, Alberti M, Hearst JE, et al. (2001) Recombinational and mutagenic repair of psoralen interstrand cross-links in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 276: 31551-60
Eichman BF, Mooers BH, Alberti M, et al. (2001) The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions. Journal of Molecular Biology. 308: 15-26
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