Irwin A. Rose
Affiliations: | University of California, Irvine, Irvine, CA |
Area:
BiochemistryWebsite:
http://nobelprize.org/nobel_prizes/chemistry/laureates/2004/rose.htmlGoogle:
"Irwin A. Rose"Bio:
(1926 - 2015)
http://www.nasonline.org/member-directory/members/51096.html
http://www.nbcnews.com/news/us-news/2004-nobel-chemistry-winner-irwin-rose-dies-88-n368836
The Nobel Prize in Chemistry 2004 was awarded jointly to Aaron Ciechanover, Avram Hershko and Irwin Rose "for the discovery of ubiquitin-mediated protein degradation".
Mean distance: 7.92 | S | N | B | C | P |
Parents
Sign in to add mentorBirgit Vennesland | grad student | 1952 | Chicago | |
(Studies of the biochemical synthesis of nucleic acids) | ||||
Charles E. Carter | post-doc | Western Reserve University | ||
Severo Ochoa | post-doc | NYU |
Children
Sign in to add traineeArthur L. Haas | grad student | Northwestern Univ Medical School | |
Gustav Edward Lienhard | grad student | 1964 | Yale |
Aaron Ciechanover | grad student | 1978-1981 | Fox Chase Cancer Center |
Frank Solomon | post-doc | 1971 | Fox Chase Cancer Center |
Cecile M. Pickart | post-doc | 1985 | Fox Chase Cancer Center |
Judith Pollock Klinman | research scientist | Fox Chase Cancer Center | |
John P. Richard | research scientist | 1982-1984 | Fox Chase Cancer Center (Crystallography Tree) |
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Publications
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Rose I. (2006) Ubiquitin at Fox Chase: Nobel lecture Israel Journal of Chemistry. 46: 107-111 |
Rose I. (2005) Ubiquitin at fox chase (Nobel Lecture) Angewandte Chemie - International Edition. 44: 5927-5931 |
Rose I. (2005) Ubiquitin in Fox Chase (Nobel-Vortrag) Angewandte Chemie. 117: 6076-6081 |
Rose IA, Weaver TM. (2004) The role of the allosteric B site in the fumarase reaction. Proceedings of the National Academy of Sciences of the United States of America. 101: 3393-7 |
Rose IA, Nowick JS. (2002) Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. Journal of the American Chemical Society. 124: 13047-52 |
Rose IA, Warms JV, Yuan RG. (1993) Role of conformational change in the fumarase reaction cycle. Biochemistry. 32: 8504-11 |
Kuo DJ, Rose IA. (1993) Mechanism of proton abstraction in biotin-dependent carboxylation reactions Journal of the American Chemical Society. 115: 387-390 |
Hadari T, Warms JV, Rose IA, et al. (1992) A ubiquitin C-terminal isopeptidase that acts on polyubiquitin chains. Role in protein degradation. The Journal of Biological Chemistry. 267: 719-27 |
Seeholzer SH, Jaworowski A, Rose IA. (1991) Enolpyruvate: chemical determination as a pyruvate kinase intermediate. Biochemistry. 30: 727-32 |
Hershko A, Rose IA. (1987) Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes. Proceedings of the National Academy of Sciences of the United States of America. 84: 1829-33 |