Irwin A. Rose

University of California, Irvine, Irvine, CA 
"Irwin A. Rose"

(1926 - 2015)
The Nobel Prize in Chemistry 2004 was awarded jointly to Aaron Ciechanover, Avram Hershko and Irwin Rose "for the discovery of ubiquitin-mediated protein degradation".

Mean distance: 7.92


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Birgit Vennesland grad student 1952 Chicago
 (Studies of the biochemical synthesis of nucleic acids)
Charles E. Carter post-doc Western Reserve University
Severo Ochoa post-doc NYU
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Rose I. (2006) Ubiquitin at Fox Chase: Nobel lecture Israel Journal of Chemistry. 46: 107-111
Rose I. (2005) Ubiquitin at fox chase (Nobel Lecture) Angewandte Chemie - International Edition. 44: 5927-5931
Rose I. (2005) Ubiquitin in Fox Chase (Nobel-Vortrag) Angewandte Chemie. 117: 6076-6081
Rose IA, Weaver TM. (2004) The role of the allosteric B site in the fumarase reaction. Proceedings of the National Academy of Sciences of the United States of America. 101: 3393-7
Rose IA, Nowick JS. (2002) Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. Journal of the American Chemical Society. 124: 13047-52
Rose IA, Warms JV, Yuan RG. (1993) Role of conformational change in the fumarase reaction cycle. Biochemistry. 32: 8504-11
Kuo DJ, Rose IA. (1993) Mechanism of proton abstraction in biotin-dependent carboxylation reactions Journal of the American Chemical Society. 115: 387-390
Hadari T, Warms JV, Rose IA, et al. (1992) A ubiquitin C-terminal isopeptidase that acts on polyubiquitin chains. Role in protein degradation. The Journal of Biological Chemistry. 267: 719-27
Seeholzer SH, Jaworowski A, Rose IA. (1991) Enolpyruvate: chemical determination as a pyruvate kinase intermediate. Biochemistry. 30: 727-32
Hershko A, Rose IA. (1987) Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes. Proceedings of the National Academy of Sciences of the United States of America. 84: 1829-33
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