Irwin A. Rose

University of California, Irvine, Irvine, CA 
"Irwin A. Rose"

(1926 - 2015)
The Nobel Prize in Chemistry 2004 was awarded jointly to Aaron Ciechanover, Avram Hershko and Irwin Rose "for the discovery of ubiquitin-mediated protein degradation".

Mean distance: 7.92


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Birgit Vennesland grad student 1952 Chicago
 (Studies of the biochemical synthesis of nucleic acids)
Severo Ochoa post-doc NYU
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Rose IA. (2006) Mechanistic inferences from stereochemistry. The Journal of Biological Chemistry. 281: 6117-9
Rose IA. (2005) Ubiquitin at Fox Chase. Proceedings of the National Academy of Sciences of the United States of America. 102: 11575-7
Rose IA, Weaver TM. (2004) The role of the allosteric B site in the fumarase reaction. Proceedings of the National Academy of Sciences of the United States of America. 101: 3393-7
Rose IA, Nowick JS. (2002) Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. Journal of the American Chemical Society. 124: 13047-52
Rose IA. (1998) How fumarase recycles after the malate --> fumarate reaction. Insights into the reaction mechanism. Biochemistry. 37: 17651-8
Rose IA. (1997) Restructuring the active site of fumarase for the fumarate to malate reaction. Biochemistry. 36: 12346-54
Rose IA. (1995) Partition analysis: detecting enzyme reaction cycle intermediates. Methods in Enzymology. 249: 315-40
Rose IA. (1995) Isotopic strategies for the study of enzymes. Protein Science : a Publication of the Protein Society. 4: 1430-3
Rose IA, Warms JV, Yuan RG. (1993) Role of conformational change in the fumarase reaction cycle. Biochemistry. 32: 8504-11
Kuo DJ, Rose IA. (1993) Mechanism of proton abstraction in biotin-dependent carboxylation reactions Journal of the American Chemical Society. 115: 387-390
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