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David R. Kearns

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
biophysical chemistry
Website:
http://www-chem.ucsd.edu/faculty/profiles/kearns_david_r.html
Google:
"David Kearns"
Mean distance: 8.03
 
SNBCP

Parents

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Melvin Calvin grad student 1959 UC Berkeley
 (Electric and Magnetic Properties of Organic Molecular Crystals)

Children

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Juli Feigon grad student 1982 UCSD
David R. Brown post-doc UCSD
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Publications

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Liu W, Vu HM, Geiduschek EP, et al. (2000) Solution structure of a mutant of transcription factor 1: implications for enhanced DNA binding. Journal of Molecular Biology. 302: 821-30
Vu HM, Liu W, Grove A, et al. (2000) Mechanisms for the enhanced thermal stability of a mutant of transcription factor 1 as explained by (1)H, (15)N and (13)C NMR chemical shifts and secondary structure analysis. Biochimica Et Biophysica Acta. 1478: 113-24
Jia X, Grove A, Ivancic M, et al. (1996) Structure of the Bacillus subtilis phage SPO1-encoded type II DNA-binding protein TF1 in solution. Journal of Molecular Biology. 263: 259-68
Hsu VL, Jia X, Kearns DR. (1995) Multidimensional NMR spectroscopy of DNA-binding proteins: structure and function of a transcription factor. Toxicology Letters. 82: 577-89
Brown DR, Kurz M, Kearns DR, et al. (1994) Formation of multiple complexes between actinomycin D and a DNA hairpin: structural characterization by multinuclear NMR. Biochemistry. 33: 651-64
Jia X, Reisman JM, Hsu VL, et al. (1994) Proton and nitrogen NMR sequence-specific assignments and secondary structure determination of the Bacillus subtilis SPO1-encoded transcription factor 1. Biochemistry. 33: 8842-52
Reisman JM, Hsu VL, Jariel-Encontre I, et al. (1993) A 1H-NMR study of the transcription factor 1 from Bacillus subtilis phage SPO1 by selective 2H-labeling. Complete assignment and structural analysis of the aromatic resonances for a 22-kDa homodimer. European Journal of Biochemistry / Febs. 213: 865-73
Tsang P, Kearns DR, Vold RR. (1992) Deuterium quadrupole echo NMR spectra and spin-lattice relaxation of synthetic polyribonucleotides Journal of the American Chemical Society. 114: 6585-6587
Ni Y, Siegel JS, Hsu VL, et al. (1991) Torsional angle and conformation in 2-vinylanthracene studied by NMR spectroscopy and MO calculations Journal of Physical Chemistry. 95: 9211-9213
Härd T, Sayre MH, Geiduschek EP, et al. (1989) A type II DNA-binding protein genetically engineered for fluorescence spectroscopy: the "arm" of transcription factor 1 binds in the DNA grooves. Biochemistry. 28: 2813-9
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