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Christopher L. Brett, Ph.D. M.D.

Affiliations: 
Biology Concordia University (Canada), Montreal, Canada 
Area:
Ion transport, pH regulation, endocytosis, membrane fusion, synaptic plasticity
Website:
http://www.brettlab.org/
Google:
"Christopher Brett Concordia Montreal"
Mean distance: 9.89 (cluster 56)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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John Church grad student 1996-1999 UBC (Neurotree)
Mark Donowitz grad student 1999-2005 Johns Hopkins (Neurotree)
 (pHome, sodium /hydrogen exchange and vesicle trafficking.)
Rajini Rao grad student 1999-2005 Johns Hopkins (Neurotree)
 (pHome, sodium /hydrogen exchange and vesicle trafficking.)
Alexey J. Merz post-doc 2005-2010 UW Medical School
BETA: Related publications

Publications

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Bögershausen N, Shahrzad N, Chong JX, et al. (2013) Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. American Journal of Human Genetics. 93: 181-90
Khorsand B, Lapointe G, Brett C, et al. (2013) Intracellular drug delivery nanocarriers of glutathione-responsive degradable block copolymers having pendant disulfide linkages Biomacromolecules. 14: 2103-2111
Lockshon D, Olsen CP, Brett CL, et al. (2012) Rho signaling participates in membrane fluidity homeostasis. Plos One. 7: e45049
Lo SY, Brett CL, Plemel RL, et al. (2012) Intrinsic tethering activity of endosomal Rab proteins. Nature Structural & Molecular Biology. 19: 40-7
Kallay LM, Brett CL, Tukaye DN, et al. (2011) Endosomal Na+ (K+)/H+ exchanger Nhx1/Vps44 functions independently and downstream of multivesicular body formation. The Journal of Biological Chemistry. 286: 44067-77
Brett CL, Kallay L, Hua Z, et al. (2011) Genome-wide analysis reveals the vacuolar pH-stat of Saccharomyces cerevisiae. Plos One. 6: e17619
Plemel RL, Lobingier BT, Brett CL, et al. (2011) Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic. Molecular Biology of the Cell. 22: 1353-63
Brett CL, Plemel RL, Lobingier BT, et al. (2011) Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase Journal of Cell Biology. 195: 1061
Nickerson DP, Brett CL, Merz AJ. (2009) Vps-C complexes: gatekeepers of endolysosomal traffic. Current Opinion in Cell Biology. 21: 543-51
Brett CL, Plemel RL, Lobingier BT, et al. (2008) Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. The Journal of Cell Biology. 182: 1141-51
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