K. C. Nicolaou
Affiliations: | 1989-2013 | Scripps Research Institute, La Jolla, La Jolla, CA, United States | |
2013- | Rice University, Houston, TX |
Area:
chemistry, biology, and medicine of natural and designed moleculesWebsite:
http://chemistry.rice.edu/FacultyDetail.aspx?p=736D6ADC0CF5EA6CGoogle:
"Kyriacos C. Nicolaou"Bio:
http://www.nasonline.org/member-directory/members/3001522.html
http://news.rice.edu/2012/09/20/chemist-k-c-nicolaou-to-join-rice-u-faculty/
http://www.scripps.edu/chem/nicolaou/KC.htm
http://www.scripps.edu/nicolaou/images/classes.htm
http://nicolaou.rice.edu/kcn.html
Mean distance: 6.67 | S | N | B | C | P |
Parents
Sign in to add mentorPeter J. Garratt | grad student | 1972 | UCL |
Franz Sondheimer | grad student | 1972 | UCL |
Thomas J. Katz | post-doc | 1972-1973 | Columbia |
Elias James Corey | post-doc | 1973-1976 | Harvard |
Children
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Publications
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Nicolaou KC, Pan S, Shelke Y, et al. (2022) A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208938119 |
Nicolaou KC, Yu R, Lu Z, et al. (2022) Total Synthesis of Gukulenin B via Sequential Tropolone Functionalizations. Journal of the American Chemical Society |
Nicolaou KC, Pan S, Shelke Y, et al. (2021) A Highly Convergent Total Synthesis of Norhalichondrin B. Journal of the American Chemical Society |
Nicolaou KC, Rigol S, Pitsinos EN, et al. (2021) Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect. Proceedings of the National Academy of Sciences of the United States of America. 118 |
Nicolaou KC, Pan S, Shelke Y, et al. (2021) A Reverse Approach to the Total Synthesis of Halichondrin B. Journal of the American Chemical Society |
Nicolaou KC, Pan S, Pulukuri KK, et al. (2021) Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis. The Journal of Organic Chemistry |
Nicolaou KC, Rekula SR, Kumar SM, et al. (2021) Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs. The Journal of Organic Chemistry |
Nicolaou KC, Chen Q, Li R, et al. (2020) Total Synthesis of the Monomeric Unit of Lomaiviticin A. Journal of the American Chemical Society. 142: 20201-20207 |
Nicolaou KC, Krieger J, Murhade GM, et al. (2020) Streamlined Symmetrical Total Synthesis of Disorazole B and Design, Synthesis, and Biological Investigation of Disorazole Analogues. Journal of the American Chemical Society |
Nicolaou KC, Li R, Chen Q, et al. (2020) Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-Drugs and Antibody-Drug Conjugates. Journal of the American Chemical Society |