K. C. Nicolaou
Affiliations: | 1989-2013 | Scripps Research Institute, La Jolla, La Jolla, CA, United States | |
| 2013- | Rice University, Houston, TX |
Area:
chemistry, biology, and medicine of natural and designed moleculesWebsite:
http://chemistry.rice.edu/FacultyDetail.aspx?p=736D6ADC0CF5EA6CGoogle:
"Kyriacos C. Nicolaou"Bio:
Shared the Wolf Prize in Chemistry 2016 for "advancing the field of chemical synthesis to the extremes of molecular complexity, linking structure and function and expanding our dominion over the interface of chemistry, biology and medicine.”
http://www.nasonline.org/member-directory/members/3001522.html
http://news.rice.edu/2012/09/20/chemist-k-c-nicolaou-to-join-rice-u-faculty/
http://www.scripps.edu/chem/nicolaou/KC.htm
http://www.scripps.edu/nicolaou/images/classes.htm
http://nicolaou.rice.edu/kcn.html
Mean distance: 6.67 | S | N | B | C | P |
Parents
Sign in to add mentor| Peter J. Garratt | grad student | 1972 | UCL |
| Franz Sondheimer | grad student | 1972 | UCL |
| Thomas J. Katz | post-doc | 1972-1973 | Columbia |
| Elias James Corey | post-doc | 1973-1976 | Harvard |
Children
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Publications
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| Nicolaou KC, Verdine GL. (2024) 30 anniversary of Cell Chemical Biology: A conversation with founding editors K.C. Nicolaou and Gregory Verdine. Cell Chemical Biology. 31: 3-5 |
| Nicolaou KC, Pan S, Shelke Y, et al. (2022) A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208938119 |
| Nicolaou KC, Yu R, Lu Z, et al. (2022) Total Synthesis of Gukulenin B via Sequential Tropolone Functionalizations. Journal of the American Chemical Society |
| Nicolaou KC, Pan S, Shelke Y, et al. (2021) A Highly Convergent Total Synthesis of Norhalichondrin B. Journal of the American Chemical Society |
| Nicolaou KC, Rigol S, Pitsinos EN, et al. (2021) Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Nicolaou KC, Pan S, Shelke Y, et al. (2021) A Reverse Approach to the Total Synthesis of Halichondrin B. Journal of the American Chemical Society |
| Nicolaou KC, Pan S, Pulukuri KK, et al. (2021) Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis. The Journal of Organic Chemistry |
| Nicolaou KC, Rekula SR, Kumar SM, et al. (2021) Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs. The Journal of Organic Chemistry |
| Nicolaou KC, Chen Q, Li R, et al. (2020) Total Synthesis of the Monomeric Unit of Lomaiviticin A. Journal of the American Chemical Society. 142: 20201-20207 |
| Nicolaou KC, Krieger J, Murhade GM, et al. (2020) Streamlined Symmetrical Total Synthesis of Disorazole B and Design, Synthesis, and Biological Investigation of Disorazole Analogues. Journal of the American Chemical Society |