David C. Myles

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Organic Chemistry
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"David Myles"
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Publications

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Zhang Q, Jing Y, Myles DC, et al. (2013) Carboalumination-epoxide ring opening for the formation of 1,4-disubstituted (Z)-3,6-alkadienols Chinese Journal of Chemistry. 31: 773-778
Liu Y, Carreras CW, Claypool M, et al. (2011) The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. Bioorganic & Medicinal Chemistry Letters. 21: 3712-4
Liu Y, Li Y, Myles DC, et al. (2010) 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. Bioorganic & Medicinal Chemistry. 18: 7651-8
Liu Y, Li Y, Chen Y, et al. (2010) 9-Dihydroerythromycins as non-antibiotic motilin receptor agonists. Bioorganic & Medicinal Chemistry Letters. 20: 5658-61
Shaw SJ, Chen Y, Zheng H, et al. (2009) Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety. Journal of Medicinal Chemistry. 52: 6851-9
Tian ZQ, Wang Z, MacMillan KS, et al. (2009) Potent cytotoxic C-11 modified geldanamycin analogues. Journal of Medicinal Chemistry. 52: 3265-73
Tian ZQ, Wang Z, Xu Y, et al. (2008) Investigating amine derivatives of ambruticin VS-5 and VS-4. Chemmedchem. 3: 963-9
Shaw SJ, Menzella HG, Myles DC, et al. (2007) Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product--a further simplification of the lactone region. Organic & Biomolecular Chemistry. 5: 2753-5
Hearn BR, Zhang D, Li Y, et al. (2006) C-15 thiazol-4-yl analogues of (E)-9,10-didehydroepothilone D: synthesis and cytotoxicity. Organic Letters. 8: 3057-9
Hearn BR, Arslanian RL, Fu H, et al. (2006) Methanolysis products of disorazole A1. Journal of Natural Products. 69: 148-50
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