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Sidney M. Hecht, Ph.D.

Affiliations: 
1978-2008 Chemistry University of Virginia, Charlottesville, VA 
 2009- BioDesign Institute Arizona State University, Tempe, AZ, United States 
Area:
Natural products, Bleomycin
Website:
http://chem.virginia.edu/faculty-research/emeritus-faculty/sidney-hecht/
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"Sidney Hecht"
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Parents

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Nelson J. Leonard grad student 1970 UIUC
 (The basis and scope of cytokinin activity)

Children

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John W. Kozarich grad student 1971-1974 MIT
Eric C. Long grad student 1984-1988 UVA
Mark Overhand grad student 1994 UVA
Anil Thomas Abraham grad student 2000 UVA
Edward Peyton Locke grad student 2000 UVA
Bixun Wang grad student 2001 UVA
Raymond D. Anderson grad student 2003 UVA
Christopher Joseph Leitheiser grad student 2003 UVA
Michael J. Rishel grad student 2004 UVA
Ali Cagir grad student 2005 UVA
Rong Gao grad student 2005 UVA
Shana K. Mattson grad student 2006 UVA
Mark A. Elban grad student 2007 UVA
Benjamin R. Schroeder grad student 2008 UVA
Ryan Matthew Schmaltz grad student 2010 UVA
Xiaoqing Cai grad student 2011 Arizona State
David M. Fash grad student 2011 UVA
Paul A. Zaleski grad student 2011 UVA
Pablo M. Arce Amezquita grad student 2012 Arizona State
Trevor C. Bozeman grad student 2013 Arizona State
Rumit Maini grad student 2013 Arizona State
Manikandadas Mathilakathu Madathil grad student 2013 Arizona State
Rakesh Paul grad student 2007-2013 Arizona State
Mohammad Parvez Alam grad student 2014 Arizona State
Jose I. Armendariz Guajardo grad student 2014 Arizona State
Basab Roy grad student 2014 Arizona State
Chandrabali Bhattacharya grad student 2009-2015 Arizona State
Sandipan Roy Chowdhury grad student 2016 Arizona State
Ulrich Jordis post-doc 1975-1976 MIT
Michael Bryant Smith post-doc 1978-1979 MIT
Nour Eddine Fahmi post-doc 1998-2001 UVA
Jia Zhou post-doc 1999-2001

Collaborators

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David G. I. Kingston collaborator 2000-2007 Virginia
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Publications

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Daskalova SM, Dedkova LM, Maini R, et al. (2023) Elongation Factor P Modulates the Incorporation of Structurally Diverse Noncanonical Amino Acids into Dihydrofolate Reductase. Journal of the American Chemical Society
Hui C, Tomilov A, Garcia C, et al. (2020) Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 132: 110823
Daskalova SM, Eisenhauer BM, Gao M, et al. (2020) An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding. Bioorganic & Medicinal Chemistry. 28: 115642
Zhang C, Chen S, Dedkova LM, et al. (2020) Effects of Nucleobase Amino Acids on the Binding of Rob to its Promoter DNA: Differential Alteration of DNA Affinity and Phenotype. Biochemistry
Zhang C, Chen S, Bai X, et al. (2020) Alteration of Transcriptional Regulator Rob In Vivo: Enhancement of Promoter DNA Binding and Antibiotic Resistance in the Presence of Nucleobase Amino Acids. Biochemistry
Dedkova LM, Hecht SM. (2019) Expanding the Scope of Protein Synthesis Using Modified Ribosomes. Journal of the American Chemical Society
Chen S, Ji X, Gao M, et al. (2019) In Cellulo Synthesis of Proteins Containing a Fluorescent Oxazole Amino Acid. Journal of the American Chemical Society
Khdour OM, Bandyopadhyay I, Visavadiya NP, et al. (2018) Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells. Medchemcomm. 9: 1491-1501
Bandyopadhyay I, Chowdhury SR, Visavadiya NP, et al. (2018) Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels. Data in Brief. 20: 1105-1114
Khdour OM, Bandyopadhyay I, Chowdhury SR, et al. (2018) Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia. Bioorganic & Medicinal Chemistry
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