Ad P. IJzerman

Affiliations: 
Leiden University, Leiden, Netherlands 
Area:
Pharmacochemistry
Website:
https://hoogleraren.leidenuniv.nl/id/3592
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"Ad IJzerman"
Mean distance: 14.62
 
SNBCP

Parents

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Henk Timmerman grad student 1985 VU Amsterdam
 (The β‐adrenoceptor complex; requirements for the interaction with its ligands)

Children

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Gerard JP van Westen grad student 2007-2012

Collaborators

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Kenneth A. Jacobson collaborator 1992- Leiden
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Publications

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Burggraaff L, van Veen A, Lam CC, et al. (2020) Annotation of Allosteric Compounds to Enhance Bioactivity Modeling for Class A GPCRs. Journal of Chemical Information and Modeling
Yang X, Dilweg MA, Osemwengie D, et al. (2020) Design and Pharmacological Profile of a Novel Covalent Partial Agonist for the Adenosine A Receptor. Biochemical Pharmacology. 114144
Wang X, Jespers W, Bongers BJ, et al. (2020) Characterization of cancer-related somatic mutations in the adenosine A receptor. European Journal of Pharmacology. 173126
Burggraaff L, Lenselink EB, Jespers W, et al. (2020) Successive Statistical and Structure-Based Modeling to Identify Chemically Novel Kinase Inhibitors. Journal of Chemical Information and Modeling
Ortiz Zacarías NV, van Veldhoven JPD, den Hollander LS, et al. (2019) Synthesis and pharmacological evaluation of triazolo-pyrimidinone derivatives as noncompetitive, intracellular antagonists for CC chemokine receptors 2 and 5. Journal of Medicinal Chemistry
Massink A, Amelia T, Karamychev A, et al. (2019) Allosteric modulation of G protein-coupled receptors by amiloride and its derivatives. Perspectives for drug discovery? Medicinal Research Reviews. 40: 683-708
Bouzo-Lorenzo M, Stoddart LA, Xia L, et al. (2019) A live cell NanoBRET binding assay allows the study of ligand-binding kinetics to the adenosine A receptor. Purinergic Signalling
Yun Y, Chen J, Liu R, et al. (2019) Long residence time adenosine A receptor agonists produce sustained wash-resistant antilipolytic effect in rat adipocytes. Biochemical Pharmacology
Yang X, van Veldhoven JPD, Offringa J, et al. (2019) Development of covalent ligands for G protein-coupled receptors: a case for the human adenosine A receptor. Journal of Medicinal Chemistry
van der Putten C, Veth J, Sukurova L, et al. (2019) TLR-Induced IL-12 and CCL2 Production by Myeloid Cells Is Dependent on Adenosine A Receptor-Mediated Signaling. Journal of Immunology (Baltimore, Md. : 1950)
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