Ad P. IJzerman

Affiliations: 
Leiden University, Leiden, Netherlands 
Area:
Pharmacochemistry
Website:
https://hoogleraren.leidenuniv.nl/id/3592
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"Ad IJzerman"
Mean distance: 14.62
 
SNBCP

Parents

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Henk Timmerman grad student 1985 VU Amsterdam
 (The β‐adrenoceptor complex; requirements for the interaction with its ligands)

Children

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Gerard JP van Westen grad student 2007-2012

Collaborators

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Kenneth A. Jacobson collaborator 1992- Leiden
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Publications

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Liu X, IJzerman AP, van Westen GJP. (2021) Computational Approaches for De Novo Drug Design: Past, Present, and Future. Methods in Molecular Biology (Clifton, N.J.). 2190: 139-165
Burggraaff L, van Veen A, Lam CC, et al. (2020) Annotation of Allosteric Compounds to Enhance Bioactivity Modeling for Class A GPCRs. Journal of Chemical Information and Modeling
Yang X, Dilweg MA, Osemwengie D, et al. (2020) Design and Pharmacological Profile of a Novel Covalent Partial Agonist for the Adenosine A Receptor. Biochemical Pharmacology. 114144
Wang X, Jespers W, Bongers BJ, et al. (2020) Characterization of cancer-related somatic mutations in the adenosine A receptor. European Journal of Pharmacology. 173126
Burggraaff L, Lenselink EB, Jespers W, et al. (2020) Successive Statistical and Structure-Based Modeling to Identify Chemically Novel Kinase Inhibitors. Journal of Chemical Information and Modeling
Superti-Furga G, Lackner D, Wiedmer T, et al. (2020) The RESOLUTE consortium: unlocking SLC transporters for drug discovery. Nature Reviews. Drug Discovery
Qile M, Ji Y, Golden TD, et al. (2020) LUF7244 plus dofetilide rescues aberrant Kv11.1 trafficking and produces functional IKv11.1. Molecular Pharmacology
Ortiz Zacarías NV, van Veldhoven JPD, den Hollander LS, et al. (2019) Synthesis and pharmacological evaluation of triazolo-pyrimidinone derivatives as noncompetitive, intracellular antagonists for CC chemokine receptors 2 and 5. Journal of Medicinal Chemistry
Oranje P, Gouka R, Burggraaff L, et al. (2019) Novel natural and synthetic inhibitors of solute carriers SGLT1 and SGLT2. Pharmacology Research & Perspectives. 7: e00504
Qile M, Beekman HDM, Sprenkeler DJ, et al. (2019) LUF7244, an allosteric modulator/activator of K 11.1 channels, counteracts dofetilide-induced TdP arrhythmia in the chronic atrioventricular block dog model. British Journal of Pharmacology
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