Alexander V. Mayorov, Ph.D.

Affiliations: 
1996-2001 Chemistry University of Louisville, Louisville, KY, United States 
Area:
Organic Chemistry, Pharmaceutical Chemistry
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Frederick A. Luzzio grad student 2001 University of Louisville
 (I. Cerium(III)-mediated Grignard additions to menthylpyruvates: Asymmetric synthesis of 4'-homologated nucleosides. II. Synthetic routes to thalidomide metabolites and analogues.)
Victor J. Hruby post-doc 2001-2007 University of Arizona
Kim David Janda post-doc 2007-2009 Scripps Institute
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Publications

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Jalah R, Torres OB, Mayorov AV, et al. (2015) Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM197 Carriers. Bioconjugate Chemistry. 26: 1041-53
Matyas GR, Rice KC, Cheng K, et al. (2014) Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine. Vaccine. 32: 1473-9
Matyas GR, Mayorov AV, Rice KC, et al. (2013) Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine. 31: 2804-10
Cai M, Stankova M, Muthu D, et al. (2013) An unusual conformation of γ-melanocyte-stimulating hormone analogues leads to a selective human melanocortin 1 receptor antagonist for targeting melanoma cells. Biochemistry. 52: 752-64
Alving CR, Rao M, Steers NJ, et al. (2012) Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines. Expert Review of Vaccines. 11: 733-44
Zakhari JS, Zorrilla EP, Zhou B, et al. (2012) Oligoclonal antibody targeting ghrelin increases energy expenditure and reduces food intake in fasted mice. Molecular Pharmaceutics. 9: 281-9
Eubanks LM, Stowe GN, De Lamo Marin S, et al. (2011) Identification of α2 macroglobulin as a major serum ghrelin esterase. Angewandte Chemie (International Ed. in English). 50: 10699-702
Stowe GN, Vendruscolo LF, Edwards S, et al. (2011) A vaccine strategy that induces protective immunity against heroin. Journal of Medicinal Chemistry. 54: 5195-204
Mayorov AV, Cai M, Palmer ES, et al. (2011) Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 21: 3099-102
Moreno AY, Mayorov AV, Janda KD. (2011) Impact of distinct chemical structures for the development of a methamphetamine vaccine. Journal of the American Chemical Society. 133: 6587-95
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