Jubilee R. Stewart, Ph.D.

Affiliations: 
2004 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology
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"Jubilee Stewart"
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Catherine A. O'Brian grad student 2004 The University of Texas Graduate School of Biomedical Sciences at Houston
 (The characterization of PKC-isozyme specific EGFR-dependent Erk1/2 activation in androgen-independent prostate cancer cell lines.)
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Publications

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Stewart JR, O'Brian CA. (2005) Protein kinase C-{alpha} mediates epidermal growth factor receptor transactivation in human prostate cancer cells. Molecular Cancer Therapeutics. 4: 726-32
Stewart JR, O'Brian CA. (2004) Resveratrol antagonizes EGFR-dependent Erk1/2 activation in human androgen-independent prostate cancer cells with associated isozyme-selective PKC alpha inhibition. Investigational New Drugs. 22: 107-17
O'Brian CA, Ward NE, Chu F, et al. (2003) Irreversible inactivation of protein kinase C isozymes by thiol-reactive peptide substrate analogs. Methods in Molecular Biology (Clifton, N.J.). 233: 441-9
Stewart JR, Artime MC, O'Brian CA. (2003) Resveratrol: a candidate nutritional substance for prostate cancer prevention. The Journal of Nutrition. 133: 2440S-2443S
O'Brian CA, Ward NE, Stewart JR, et al. (2001) Prospects for targeting protein kinase C isozymes in the therapy of drug-resistant cancer--an evolving story. Cancer Metastasis Reviews. 20: 95-100
Bedikian AY, Plager C, Stewart JR, et al. (2001) Phase II evaluation of bryostatin-1 in metastatic melanoma. Melanoma Research. 11: 183-8
Stewart JR, Christman KL, O'Brian CA. (2000) Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation. Biochemical Pharmacology. 60: 1355-9
Ward NE, Stewart JR, Ioannides CG, et al. (2000) Oxidant-induced S-glutathiolation inactivates protein kinase C-alpha (PKC-alpha): a potential mechanism of PKC isozyme regulation. Biochemistry. 39: 10319-29
Stewart JR, Ward NE, Ioannides CG, et al. (1999) Resveratrol preferentially inhibits protein kinase C-catalyzed phosphorylation of a cofactor-independent, arginine-rich protein substrate by a novel mechanism. Biochemistry. 38: 13244-51
Ward NE, Pierce DS, Stewart JR, et al. (1999) A peptide substrate-based affinity label blocks protein kinase C-catalyzed ATP hydrolysis and peptide-substrate phosphorylation. Archives of Biochemistry and Biophysics. 365: 248-53
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