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Jason R. Buck, Ph.D.

Affiliations: 
2002 Vanderbilt University, Nashville, TN 
Area:
Organic Chemistry, Pharmaceutical Chemistry
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Carmelo Rizzo grad student 2002 Vanderbilt
 (Stereocontrolled de novo synthesis of 2',3'-dideoxynucleosides via photoinduced electron transfer deoxygenation.)

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Cheung YY, Nickels ML, Tang D, et al. (2014) Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer. Bioorganic & Medicinal Chemistry Letters. 24: 4466-71
Uddin MI, Buck JR, Schulte ML, et al. (2014) Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes. Tetrahedron Letters. 55
Cheung Y, Buck JR, Nickels ML, et al. (2014) Abstract 110: Preclinical evaluation of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[18F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide: A novel pyridazinoindole ligand for PET imaging of TSPO in cancer Cancer Research. 74: 110-110
Tang D, McKinley ET, Hight MR, et al. (2013) Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging. Journal of Medicinal Chemistry. 56: 3429-33
Buck JR, Saleh S, Uddin MI, et al. (2012) Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research. Tetrahedron Letters. 53: 4161-4165
Buck JR, Saleh S, Hight MR, et al. (2012) Abstract 5743: Positron emission tomography (PET) imaging analogs of glutamine: Development and evaluation as probes for cancer imaging Cancer Research. 72: 5743-5743
Tang D, Buck JR, Hight MR, et al. (2010) Microwave-assisted Organic Synthesis of a High-affinity Pyrazolo-pyrimidinyl TSPO Ligand. Tetrahedron Letters. 51: 4595-4598
PARK M, BUCK JR, RIZZO CJ. (2010) ChemInform Abstract: A Convenient Synthesis of 3,6-Substituted Carbazoles via Nickel-Catalyzed Cross-Coupling. Cheminform. 30: no-no
Prudhomme DR, Park M, Wang Z, et al. (2003) Synthesis of 2′-Deoxyribonucleosides: β-3′,5′-Di-O-Benzoylthymidine Organic Syntheses. 162-162
Buck JR, Park M, Wang Z, et al. (2003) 9‐Ethyl‐3,6‐Dimethylcarbazole (DMECZ) Organic Syntheses. 153-153
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