James S. Stover, Ph.D.

Affiliations: 
2006 Vanderbilt University, Nashville, TN 
Area:
Biochemistry, Organic Chemistry
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Carmelo Rizzo grad student 2006 Vanderbilt
 (Synthetic, replicative, and oxidative studies of C8- and N(2)-deoxyguanosine adducts of the dietary mutagen 2-amino-3-methylimidazo[4,5-f]quinoline.)
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Publications

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Dellon E, Yellore V, Stover J. (2014) A Single Paraffin-Embedded or RNA Later-Preserved C is Valid for Genetic Diagnosis of Eosinophilic Esophagitis Regardless of Location in the Esophagus: 106 The American Journal of Gastroenterology. 109
Stover J, Yellore V, Miller A, et al. (2014) Validation of a Next-Generation Sequencing Cancer Panel for Clinical Mutation Profiling in Patients with Diffuse Large B-Cell Lymphoma (DLBCL) Blood. 124: 2997-2997
Christov PP, Chowdhury G, Garmendia CA, et al. (2010) The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Chemical Research in Toxicology. 23: 1076-88
Hauschild KE, Stover JS, Boger DL, et al. (2009) CSI-FID: high throughput label-free detection of DNA binding molecules. Bioorganic & Medicinal Chemistry Letters. 19: 3779-82
Stover JS, Shi J, Jin W, et al. (2009) Discovery of inhibitors of aberrant gene transcription from Libraries of DNA binding molecules: inhibition of LEF-1-mediated gene transcription and oncogenic transformation. Journal of the American Chemical Society. 131: 3342-8
Tichenor MS, MacMillan KS, Stover JS, et al. (2007) Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins. Journal of the American Chemical Society. 129: 14092-9
Stover JS, Rizzo CJ. (2007) Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline. Chemical Research in Toxicology. 20: 1972-9
Wang F, Elmquist CE, Stover JS, et al. (2007) DNA sequence modulates the conformation of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme. Biochemistry. 46: 8498-516
Elmquist CE, Wang F, Stover JS, et al. (2007) Conformational differences of the C8-deoxyguanosine adduct of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) within the NarI recognition sequence. Chemical Research in Toxicology. 20: 445-54
Stover JS, Ciobanu M, Cliffel DE, et al. (2007) Chemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosine. Journal of the American Chemical Society. 129: 2074-81
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