Xiaohua Shen, Ph.D.

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Genetics, Molecular Biology, Cell Biology
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"Xiaohua Shen"
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Parents

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Randal J. Kaufman grad student 2003 University of Michigan
 (Unfolding the unfolded protein response: Turn to the worm!)
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Publications

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Huang X, Bashkenova N, Hong Y, et al. (2022) A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency. Cell Reports. 39: 110928
Shao W, Bi X, Pan Y, et al. (2021) Phase separation of RNA-binding protein promotes polymerase binding and transcription. Nature Chemical Biology
Sun Z, Yu H, Zhao J, et al. (2021) LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells. Protein & Cell
Yan P, Lu JY, Niu J, et al. (2020) LncRNA Platr22 promotes super-enhancer activity and stem cell pluripotency. Journal of Molecular Cell Biology
Bi X, Zhang X, Shen X. (2020) Transcriptome-Wide Profiling of Protein-RNA Interactions by Cross-Linking and Immunoprecipitation Mediated by FLAG-Biotin Tandem Purification. Journal of Visualized Experiments : Jove
Yin Y, Lu JY, Zhang X, et al. (2020) U1 snRNP regulates chromatin retention of noncoding RNAs. Nature. 580: 147-150
Zhao J, Wang M, Chang L, et al. (2020) RYBP/YAF2-PRC1 complexes and histone H1-dependent chromatin compaction mediate propagation of H2AK119ub1 during cell division. Nature Cell Biology
Lu JY, Shao W, Chang L, et al. (2020) Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation. Cell Reports. 30: 3296-3311.e5
Zhang H, Wu Z, Lu JY, et al. (2020) DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation. Cell Reports. 30: 81-97.e7
Liu L, Lu JY, Li F, et al. (2019) IDH1 fine-tunes cap-dependent translation initiation. Journal of Molecular Cell Biology
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