George Paul Hess, A.B., Ph.D.

Affiliations: 
Molecular Biology & Genetics Cornell University, Ithaca, NY, United States 
Area:
caged neurotransmitters, photolysis, kinetics, nicotinic acetylcholine, GABA(A), NMDA, glutamate, glycine, receptors, inhibitors, epilepsy
Website:
http://www.news.cornell.edu/stories/2015/09/george-hess-biochemist-dies-92
Google:
"George P Hess"
Bio:

(1926 - 2015)
http://www.nasonline.org/member-directory/deceased-members/15525.html
http://mbg.cornell.edu/cals/mbg/faculty-staff/faculty/hess.cfm
http://www.news.cornell.edu/stories/April09/ArtsSciFellowHess.html

Mean distance: 17.74 (cluster 32)
 
SNBCP
Cross-listing: Neurotree

Children

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Tracy Milburn research assistant Cornell (Neurotree)
Peter S. Kim research assistant 1977-1979 Cornell
One Pagan grad student Cornell (Neurotree)
Satoru Shiono grad student Cornell (Neurotree)
Raymond Wieboldt grad student Cornell (Neurotree)
Pierre Leprince grad student 1977-1980 Cornell (Neurotree)
Jeffrey Karpen grad student 1985 Cornell
Anne Delcour grad student 1986 Cornell
Jayant Udgaonkar grad student 1981-1986 Cornell
Katherine Walstrom grad student 1993 Cornell
Ryan W. Lewis grad student 2011 Cornell (Neurotree)
John Andrews post-doc Cornell (Neurotree)
Hitoshi Aoshima post-doc Cornell (Neurotree)
Anamitro Banerjee post-doc Cornell (Neurotree)
Andrew Billington post-doc Cornell (Neurotree)
Hans-Georg Breitinger post-doc Cornell (Neurotree)
Derek Cash post-doc Cornell (Neurotree)
Yongli Chen post-doc Cornell (Neurotree)
Juian-juian Fu post-doc Cornell (Neurotree)
Norihisa Fujita post-doc Cornell (Neurotree)
Armanda Gameiro post-doc Cornell (Neurotree)
Natarajan Geetha post-doc Cornell (Neurotree)
Christof Grewer post-doc Cornell (Neurotree)
Vasanthi Jayaraman post-doc Cornell
Heyi Li post-doc Cornell (Neurotree)
Norio Matsubara post-doc Cornell (Neurotree)
Li Niu post-doc Cornell (Neurotree)
Elena Pasquale post-doc Cornell (Neurotree)
Latha Ramakrishnan post-doc Cornell (Neurotree)
Doraiswamy Ramesh post-doc Cornell (Neurotree)
Helga Rübsamen-Schaeff post-doc Cornell (Neurotree)
Klaus Schaper post-doc Cornell (Neurotree)
Vishakha Shembekar post-doc Cornell (Neurotree)
Kannan Sivaprakasam post-doc Cornell (Neurotree)
Sanjay Srivastava post-doc Cornell (Neurotree)
Melody Sweet post-doc Cornell (Neurotree)
Henning Ulrich post-doc Cornell (Neurotree)
Karl G. Brandt post-doc 1966 Cornell
Jeffery William Walker post-doc 1985 Cornell (Physiology Academic Tree)

Collaborators

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David M. Blow collaborator MRC-LMB
Barry K. Carpenter collaborator Cornell
Winfried Denk collaborator Cornell (Neurotree)
Vincent du Vigneaud collaborator Cornell
Thomas Fox collaborator Cornell
Bruce Ganem collaborator Cornell
Murray Goodman collaborator MIT
Peter Lauger collaborator University of Konstanz (Neurotree)
Aaron Lewis collaborator Cornell
John T. Lis collaborator Cornell
Douglas Moore collaborator Cornell (Neurotree)
Nathan Nelson collaborator Cornell
Robert Oswald collaborator Cornell
Watt W. Webb collaborator Cornell
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Publications

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Hess GP, Lewis RW, Chen Y. (2014) Caged neurotransmitters and other caged compounds: design and application. Cold Spring Harbor Protocols. 2014: pdb.top084152
Hess GP, Lewis RW, Chen Y. (2014) Cell-flow technique. Cold Spring Harbor Protocols. 2014: pdb.prot084160
Lewis RW, Hess GP, Ganem B. (2011) Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function. Future Medicinal Chemistry. 3: 243-50
Ramakrishnan L, Hess GP. (2010) Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations. Biochemistry. 49: 7892-901
Lewis RW, Mabry J, Polisar JG, et al. (2010) Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant. Biochemistry. 49: 4841-51
Sivaprakasam K, Pagán OR, Hess GP. (2010) Minimal RNA aptamer sequences that can inhibit or alleviate noncompetitive inhibition of the muscle-type nicotinic acetylcholine receptor. The Journal of Membrane Biology. 233: 1-12
Fan L, Lewis RW, Hess GP, et al. (2009) A new synthesis of caged GABA compounds for studying GABAA receptors. Bioorganic & Medicinal Chemistry Letters. 19: 3932-3
Shembekar VR, Chen Y, Carpenter BK, et al. (2007) Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light. Biochemistry. 46: 5479-84
Krivoshein AV, Hess GP. (2006) On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor. Biochemistry. 45: 11632-41
Ramakrishnan L, Hess GP. (2005) Picrotoxin inhibition mechanism of a gamma-aminobutyric acid A receptor investigated by a laser-pulse photolysis technique. Biochemistry. 44: 8523-32
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