Parents

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Thomas C. Bruice grad student 1964 Cornell
 (A comparison of bimolecular and intramolecular nucleophilic catalysis: the compensation in ΔH and ΔS accompanying the conversion of lower order nucleophilic displacement reactions to higher order catalytic processes :)

Children

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James Inglese grad student 1984-1989 Penn State (Neurotree)
Lata T. Gooljarsingh grad student 2000 Penn State
Joseph Ramcharan grad student 2001 Penn State (Neurotree)
Vincent K. Shier grad student 2001 Penn State
Michael A. Trakselis grad student 2002 Penn State
Songon An post-doc Penn State
William R Cannon post-doc Penn State
Walter Fast post-doc
Carol A. Fierke post-doc Penn State
Scott Nelson post-doc
Michael Webb post-doc
Graeme Moad post-doc 1977-1978 Penn State
Susan Colette Daubner post-doc 1982-1985
Carston R. Wagner post-doc 1987-1991 Penn State
Richard A. Gibbs post-doc 1988-1991 Penn State
Carlos F. Barbas, III post-doc 1989-1991 Scripps Institute
Louis J. Liotta post-doc 1990-1993 Penn State
Shankar Balasubramanian post-doc 1991-1993 Penn State
Michael W. Crowder post-doc 1995 Penn State
Craig Eugene Cameron post-doc 1994-1997 Penn State
Ann M. Valentine post-doc 1998-2001 Penn State
Stefan Lutz post-doc 1999-2002 Penn State
Alexander R. Horswill post-doc 2001-2005 Penn State (Microtree)
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Publications

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Doigneaux C, Pedley AM, Mistry IN, et al. (2020) Hypoxia Drives the Assembly of the Multi-Enzyme Purinosome Complex. The Journal of Biological Chemistry
Benkovic SJ. (2019) Thomas Bruice (1925-2019). Proceedings of the National Academy of Sciences of the United States of America
Perumal SK, Xu X, Yan C, et al. (2019) Recognition of a Key Anchor Residue by a Conserved Hydrophobic Pocket Ensures Subunit Interface Integrity in DNA Clamps. Journal of Molecular Biology
Liu C, Knudsen GM, Pedley AM, et al. (2019) Mapping post-translational modifications of de novo purine biosynthetic enzymes: Implications for pathway regulation. Journal of Proteome Research
Hedglin M, Aitha M, Pedley A, et al. (2019) Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen. The Journal of Biological Chemistry
Pedley AM, Benkovic SJ. (2018) Detecting Purinosome Metabolon Formation with Fluorescence Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1764: 279-289
Pedley AM, Karras GI, Zhang X, et al. (2018) The Role of HSP90 in the Regulation of de novo Purine Biosynthesis. Biochemistry
Zhao X, Palacci H, Yadav V, et al. (2018) Substrate-driven chemotactic assembly in an enzyme cascade. Nature Chemistry. 10: 311-317
Benkovic SJ, Spiering MM. (2017) Understanding DNA replication by the bacteriophage T4 replisome. The Journal of Biological Chemistry
Hedglin M, Aitha M, Benkovic SJ. (2017) Monitoring the Retention of Human PCNA at Primer/Template junctions by Proteins that Bind Single-stranded DNA. Biochemistry
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