Dale L. Boger

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
synthetic organic chemistry
Website:
http://www.scripps.edu/chem/boger/db.html
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"Dale Boger"
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Parents

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Elias James Corey grad student 1976-1979 Harvard
 (New annulation processes ; II. Studies directed toward a biomimetic syntheic approach to prostaglandins)
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Publications

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Morin MD, Wang Y, Jones BT, et al. (2018) Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists. Journal of the American Chemical Society
Wang Y, Su L, Morin MD, et al. (2018) Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice. Proceedings of the National Academy of Sciences of the United States of America
Glinkerman CM, Boger DL. (2018) Synthesis, Characterization, and Rapid Cycloadditions of 5-Nitro-1,2,3-triazine. Organic Letters
Lukesh JC, Carney DW, Dong H, et al. (2017) Vinblastine 20' Amides: Synthetic Analogues That Maintain or Improve Potency and Simultaneously Overcome Pgp-Derived Efflux and Resistance. Journal of Medicinal Chemistry
Quiñones RE, Glinkerman CM, Zhu K, et al. (2017) Direct Synthesis of β-Aminoenals through Reaction of 1,2,3-Triazine with Secondary Amines. Organic Letters
Okano A, Isley NA, Boger DL. (2017) Peripheral modifications of [Ψ[CH2NH]Tpg(4)]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics. Proceedings of the National Academy of Sciences of the United States of America
Allemann O, Cross RM, Brütsch MM, et al. (2017) Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20' ethyl substituent. Bioorganic & Medicinal Chemistry Letters
Kornahrens AF, Cognetta AB, Brody DM, et al. (2017) Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor. Journal of the American Chemical Society
Okano A, Isley NA, Boger DL. (2017) Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues. Chemical Reviews
Yang S, Sankar K, Skepper CK, et al. (2017) Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity. Chemical Science. 8: 1560-1569
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