Ralph B. Arlinghaus

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology, Biostatistics Biology, Genetics, Oncology
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"Ralph Arlinghaus"

Parents

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Milan Alexander Logan grad student 1961 University of Cincinnati (Chemistry Tree)
 (Studies on a new amino acid isolated from collagen : sequence studies of peptides obtained from enzymatic hydrolysates of collagen)
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Publications

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Chappell WH, Candido S, Abrams SL, et al. (2018) Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines. Advances in Biological Regulation
Chakraborty SN, Leng X, Perazzona B, et al. (2016) Combination of JAK2 and HSP90 inhibitors: an effective therapeutic option in drug-resistant chronic myelogenous leukemia. Genes & Cancer. 7: 201-8
Mu C, Wu X, Ma H, et al. (2016) Effective concentration of a multi-kinase inhibitor within bone marrow correlates with in vitro cell killing in therapy-resistant chronic myeloid leukemia. Molecular Cancer Therapeutics
Ochieng J, Nunomura S, Lang W, et al. (2016) Abstract 1124: Expression of the lipocalin 2 oncogene in the development of smoking-associated and Kras mutant lung adenocarcinoma Cancer Research. 76: 1124-1124
Tao W, Chakraborty SN, Leng X, et al. (2015) HSP90 inhibitor AUY922 induces cell death by disruption of the Bcr-Abl, Jak2 and HSP90 signaling network complex in leukemia cells. Genes & Cancer. 6: 19-29
Mallampati S, Leng X, Ma H, et al. (2015) Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood. 125: 2968-73
Ma H, Mallampati S, Lu Y, et al. (2014) The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia. Haematologica. 99: 1591-8
Tao W, Leng X, Chakraborty SN, et al. (2014) c-Abl activates janus kinase 2 in normal hematopoietic cells. The Journal of Biological Chemistry. 289: 21463-72
Neviani P, Harb JG, Oaks JJ, et al. (2013) PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells. The Journal of Clinical Investigation. 123: 4144-57
Oaks JJ, Santhanam R, Walker CJ, et al. (2013) Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies. Blood. 122: 1923-34
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