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Peter J. Garratt

Affiliations: 
University College London, London, United Kingdom 
Area:
Organic Chemistry and Chemical Biology
Website:
http://www.ucl.ac.uk/chemistry/staff/emeritus/peter_garratt
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"Peter Garratt"
Mean distance: 7.15
 
SNBCP

Parents

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Thomas J. Katz grad student 1964 Columbia
 (The cyclononatetraenyl ions)

Children

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K. C. Nicolaou grad student 1972 UCL
K. Peter C. Vollhardt grad student 1972 UCL
Robert M. Jones grad student 1992-1995 UCL
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Publications

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Tsotinis A, Kompogennitaki R, Papanastasiou I, et al. (2019) Fluorine substituted methoxyphenylalkyl amides as potent melatonin receptor agonists. Medchemcomm. 10: 460-464
Tsotinis A, Afroudakis PA, Garratt PJ, et al. (2014) Benzocyclobutane, benzocycloheptane and heptene derivatives as melatonin agonists and antagonists. Chemmedchem. 9: 2238-43
Garratt PJ, Tsotinis A. (2007) Synthesis of compounds as melatonin agonists and antagonists. Mini Reviews in Medicinal Chemistry. 7: 1075-88
Faust R, Garratt PJ, Trujillo Pérez MA, et al. (2007) 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity. Bioorganic & Medicinal Chemistry. 15: 4543-51
Davies DJ, Faust R, Garratt PJ, et al. (2004) Binding affinity and biological activity of oxygen and sulfur isosteres at melatonin receptors as a function of their hydrogen bonding capability. Bioorganic Chemistry. 32: 1-12
Maria Christofi A, Garratt PJ, Hogarth G, et al. (2002) Molecular design using electrostatic interactions. Part 4: Synthesis and properties of flexible tetrapodand tetracations derived from naphthalene. Role of structured water in the electrostatic binding of polyanion guests: A model for interactions in biological systems Tetrahedron. 58: 4543-4549
Faust R, Garratt PJ, Jones R, et al. (2000) Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles. Journal of Medicinal Chemistry. 43: 1050-61
Davies DJ, Garratt PJ, Tocher DA, et al. (1998) Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles. Journal of Medicinal Chemistry. 41: 451-67
Garratt PJ, Ibbett AJ, Ladbury JE, et al. (1998) Molecular design using electrostatic interactions. Part 1. Synthesis and properties of flexible tripodand tri- and hexa-cations with restricted conformations. Molecular selection of ferricyanide from ferrocyanide Tetrahedron. 54: 949-968
Garratt PJ, Travard S, Vonhoff S, et al. (1996) Mapping the melatonin receptor. 4. Comparison of the binding affinities of a series of substituted phenylalkyl amides. Journal of Medicinal Chemistry. 39: 1797-805
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