Dennis A. Dougherty

California Institute of Technology, Pasadena, CA 
physical organic chemistry to systems of biological importance
"Dennis Dougherty"

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Kurt M. Mislow grad student 1978 Princeton
 (Structural studies in polyarylethane chemistry)


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Tingwei Mu grad student Case Western
Lisa Ann McElwee-White grad student 1983 Caltech
Gary J. Snyder grad student 1988
Alison McCurdy grad student 1995 Caltech
Sandro Mecozzi grad student 1996 Caltech
Scott K. Silverman grad student 1997 Caltech
Jennifer C. Ma grad student 2000 Caltech
Justin P. Gallivan grad student 1994-2000 Caltech
Lintong Li grad student 2002 Caltech
Gabriel S. Brandt grad student 2003 Caltech
Joshua A. Maurer grad student 2003 Caltech
Darren L. Beene grad student 2004 Caltech
Donald E. Elmore grad student 2004 Caltech
Sarah L. Monahan grad student 2004 Caltech
E. James Petersson grad student 2005 Caltech
Steven A. Spronk grad student 2006 Caltech
Amy L. Eastwood grad student 2009 Caltech
Ariele P. Hanek grad student 2009 Caltech
Erik A. Rodriguez grad student 2009 Caltech
Michael M. Torrice grad student 2009 Caltech
Kristin R. Gleitsman grad student 2010 Caltech
Jai A. Shanata grad student 2011 Caltech
Angela P. Blum grad student 2012 Caltech
Nyssa L. Puskar grad student 2012 Caltech
Walrati Limapichat grad student 2013 Caltech
Kristina N. Daeffler grad student 2014 Caltech
Ethan B. Van Arnam grad student 2014 Caltech
Leslie S. Jimenez post-doc 1989-1991 Caltech
David A. Shultz post-doc 1989-1992 Caltech
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Lester HA, Dougherty DA. (2019) Nicotine Bound to Its Receptors: New Structures for a Vexing Pathopharmacological Problem. Neuron. 104: 431-432
Blom AEM, Rego Campello H, Lester HA, et al. (2019) Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor. Journal of the American Chemical Society
Mosesso R, Dougherty DA, Lummis SCR. (2019) Proline Residues in the Transmembrane/Extracellular Domain Interface Loops Have Different Behaviors in 5-HT and nACh Receptors. Acs Chemical Neuroscience. 10: 3327-3333
Shivange AV, Borden PM, Muthusamy AK, et al. (2019) Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. The Journal of General Physiology
Henderson BJ, Grant S, Chu BW, et al. (2018) Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing. Eneuro. 5
Mosesso R, Dougherty DA, Lummis SCR. (2018) Probing Proline Residues in the Prokaryotic Ligand-Gated Ion Channel, ELIC. Biochemistry
Post MR, Tender GS, Lester HA, et al. (2017) Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors. Eneuro. 4
Post M, Lester HA, Dougherty DA. (2017) Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors. Biochemistry
Nichols WA, Henderson BJ, Marotta CB, et al. (2016) Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression. Plos One. 11: e0158032
Rienzo M, Rocchi AR, Threatt SD, et al. (2015) Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-Gated Ion Channel (GLIC) Supports Conserved Gating Motions Among Cys-Loop Receptors. The Journal of Biological Chemistry
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