Robert Heinz Abeles, Ph.D.

Affiliations: 
1957-1960 Ohio State University, Columbus, Columbus, OH 
 1960-1964 University of Michigan, Ann Arbor, Ann Arbor, MI 
 1964-2000 Brandeis University, Waltham, MA, United States 
Area:
mechanistic enzymology
Website:
https://www.acsmedchem.org/?nd=Abeles
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"Robert H. Abeles"
Bio:

(1926 - 2000)
http://www.nasonline.org/member-directory/deceased-members/58405.html

Mean distance: 6.77
 
SNBCP
Cross-listing: MichiganTree

Parents

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Cosmo G. Mackenzie grad student 1955 CU Boulder
 (The enzymatic oxidation of sarcosine-N-methyl-D3)
Frank H. Westheimer post-doc 1957 Harvard

Children

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Perry A. Frey grad student 1968 Brandeis
Gary Rudnick grad student 1969-1973 Brandeis
Karen N. Allen grad student 1984-1989 Brandeis
Robert A. Arkowitz grad student 1986-1991 Brandeis (Cell Biology Tree)
Gary Frey grad student 2000 Brandeis
Bruce A. Averill post-doc Brandeis
Richard B. Silverman post-doc
Ronald H. Kluger post-doc 1969-1970 Brandeis
Christopher  T. Walsh post-doc 1970-1972 Brandeis
JoAnne Stubbe post-doc 1975-1977 Brandeis
Michael H. Gelb post-doc 1985 Brandeis
Barbara Imperiali post-doc 1986 Brandeis
Pradipsinh K. Rathod post-doc 1982-1986 Brandeis
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Publications

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Weil M, Abeles R, Nachmany A, et al. (2004) Folic acid rescues nitric oxide-induced neural tube closure defects [3] Cell Death and Differentiation. 11: 361-363
Huang X, Knoell CT, Frey G, et al. (2001) Modulation of recombinant human prostate-specific antigen: activation by Hofmeister salts and inhibition by azapeptides. Appendix: thermodynamic interpretation of the activation by concentrated salts. Biochemistry. 40: 11734-41
Dai Y, Pochapsky TC, Abeles RH. (2001) Mechanistic studies of two dioxygenases in the methionine salvage pathway of Klebsiella pneumoniae. Biochemistry. 40: 6379-87
Dai Y, Hedstrom L, Abeles RH. (2000) Inactivation of cysteine proteases by (acyloxy)methyl ketones using S'-P' interactions. Biochemistry. 39: 6498-502
Dai Y, Wensink PC, Abeles RH. (1999) One protein, two enzymes. The Journal of Biological Chemistry. 274: 1193-5
Govardhan CP, Abeles RH. (1996) Inactivation of cysteine proteases. Archives of Biochemistry and Biophysics. 330: 110-4
Baggio R, Shi YQ, Wu YQ, et al. (1996) From poor substrates to good inhibitors: Design of inhibitors for serine and thiol proteases Biochemistry. 35: 3351-3353
Wu Y, Abeles RH. (1995) Protease assay based on magnetic beads. Analytical Biochemistry. 229: 143-4
Wray JW, Abeles RH. (1995) The methionine salvage pathway in Klebsiella pneumoniae and rat liver. Identification and characterization of two novel dioxygenases. The Journal of Biological Chemistry. 270: 3147-53
Bastos M, Maeji NJ, Abeles RH. (1995) Inhibitors of human heart chymase based on a peptide library. Proceedings of the National Academy of Sciences of the United States of America. 92: 6738-42
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