Daniel E. Kahne

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
molecular mechanisms of various antibiotics
Website:
http://www.chem.harvard.edu/groups/kahne/index.html
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"Daniel Kahne"
Bio:

https://news.harvard.edu/gazette/story/2004/11/kahne-brings-chemistry-to-life/

Mean distance: 7.2
 
SNBCP

Parents

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Gilbert Stork grad student 1986 Columbia
 (Part I. Hydroxyl directed homogeneous hydrogenation using a catalytic iridium complex ; Part II. An approach to the synthesis of tetracycline)
W. Clark Still post-doc 1988 Columbia

Children

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Jeffrey Gildersleeve grad student
Ran Xie grad student
Dan Yang grad student 1991 Princeton
Amy H. Andreotti grad student 1994 Princeton
Kaustav Biswas grad student 2000 Princeton
Hayley A. Xuereb grad student 2000 Princeton
Zhong Chen grad student 2001 Princeton
Kimberly M. Specht grad student 2002 Princeton
Brian V. Falcone grad student 2004 Princeton
John V. LaTour grad student 2004 Princeton
Joonwoo Nam grad student 2004 Princeton
Binyuan Sun grad student 2004 Princeton
Christopher D. Brander grad student 2005 Princeton
Catherine E. Leimkuhler grad student 2006 Harvard
Scott A. McMurry grad student 2006 Princeton
Hak S. Chung grad student 2007 Harvard
Xuechen Li grad student 2007 Harvard
Seokhee Kim grad student 2008 Harvard
Wenjiang Zhu grad student 2008 Harvard
Shu S. Chng grad student 2010 Harvard
Michael B. Lazarus grad student 2010 Harvard
Emma H. Doud grad student 2011 Harvard
Tania J. Lupoli grad student 2011 Harvard
Tsung-Shing Wang grad student 2011 Harvard
Craig Braun grad student 2012 Harvard
Elizaveta Freinkman grad student 2012 Harvard
Christine L. Hagan grad student 2012 Harvard
Yihui Wu grad student 2012 Harvard
Zhizhong Yao grad student 2012 Harvard
John Janetzko grad student 2012-2017 Harvard
Frederick A Rubino grad student 2012-2019 Harvard
Matthew D. Lebar post-doc 2011- Harvard
Amit Basu post-doc 1996-1999 Princeton

Collaborators

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Suzanne Walker collaborator
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Publications

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Tomasek D, Rawson S, Lee J, et al. (2020) Structure of a nascent membrane protein as it folds on the BAM complex. Nature
Sjodt M, Rohs PDA, Gilman MSA, et al. (2020) Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex. Nature Microbiology
Rubino FA, Mollo A, Kumar S, et al. (2020) Detection of transport intermediates in the peptidoglycan flippase MurJ identifies residues essential for conformational cycling. Journal of the American Chemical Society
Do T, Schaefer K, Santiago AG, et al. (2020) Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan. Nature Microbiology
Lee J, Tomasek D, Santos T, et al. (2019) Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA. Elife. 8
Taguchi A, Kahne D, Walker S. (2019) Chemical tools to characterize peptidoglycan synthases. Current Opinion in Chemical Biology. 53: 44-50
Simpson BW, Pahil KS, Owens TW, et al. (2019) Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport. Mbio. 10
Welsh MA, Schaefer K, Taguchi A, et al. (2019) The direction of chain growth and substrate preferences of SEDS-family peptidoglycan glycosyltransferases. Journal of the American Chemical Society
Owens TW, Taylor RJ, Pahil KS, et al. (2019) Structural basis of unidirectional export of lipopolysaccharide to the cell surface. Nature
Hart EM, O'Connell A, Tang K, et al. (2019) Fine tuning of σ activation suppresses multiple assembly-defective mutations in . Journal of Bacteriology
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