Peter T. Lansbury

Affiliations: 
State University of New York, Buffalo, Buffalo, NY, United States 
Area:
natural products synthesis
Website:
http://www.chemistry.buffalo.edu/people/emeritus_faculty/lansbury/
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"Peter Lansbury"
Mean distance: 8.78
 
SNBCP

Parents

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Robert Lewis Letsinger grad student 1956 Northwestern
 (Rearrangements and rings closures of some peri-substituted naphthalenes)

Children

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Cheon-Gyu Cho post-doc 1993-1995 MIT
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Publications

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Cuddy LK, Wani WY, Morella ML, et al. (2019) Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. Neuron
Collier TJ, Srivastava KR, Justman C, et al. (2017) Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. Neurobiology of Disease
Vamvaca K, Volles MJ, Lansbury PT. (2009) The first N-terminal amino acids of alpha-synuclein are essential for alpha-helical structure formation in vitro and membrane binding in yeast. Journal of Molecular Biology. 389: 413-24
Paleologou KE, Schmid AW, Rospigliosi CC, et al. (2008) Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. The Journal of Biological Chemistry. 283: 16895-905
Martinez-Vicente M, Talloczy Z, Kaushik S, et al. (2008) Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. The Journal of Clinical Investigation. 118: 777-88
Fredenburg RA, Rospigliosi C, Meray RK, et al. (2007) The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states. Biochemistry. 46: 7107-18
Volles MJ, Lansbury PT. (2007) Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity. Journal of Molecular Biology. 366: 1510-22
Follmer C, Romão L, Einsiedler CM, et al. (2007) Dopamine affects the stability, hydration, and packing of protofibrils and fibrils of the wild type and variants of alpha-synuclein. Biochemistry. 46: 472-82
Lansbury PT, Lashuel HA. (2006) A century-old debate on protein aggregation and neurodegeneration enters the clinic. Nature. 443: 774-9
Lashuel HA, Lansbury PT. (2006) Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins? Quarterly Reviews of Biophysics. 39: 167-201
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