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Jeffrey D. Winkler

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
New Synthetic Pathways
Website:
http://webdev.chem.upenn.edu/chem/research/faculty.php?id=39
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"Jeffrey Winkler"
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SNBCP

Parents

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Gilbert Stork grad student 1981 Columbia
 (I. Stereochemical control in the intramolecular Michael reaction ; II. A synthesis of adrenosterone)
Ronald Charles David Breslow post-doc 1983 Columbia

Children

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Richard P. Hsung research assistant Chicago
Benjamin A. Schneider research assistant 2011- Penn
BOR-CHERNG HONG grad student 1988-1992 University of Chicago and University of Pennsylvania
Samit K Bhattacharya grad student 1991-1996 Penn
Sean J. Harrison grad student 2000 Penn
Lori Krim grad student 2001 Penn
Young-Shin Kwak grad student 2001 Penn
Daniel E. Macks grad student 2002 Penn
LaToya I. Nevels grad student 2002 Penn
Meagan B. Rouse grad student 2003 Penn
Stacey Shepard grad student 2003 Penn
Sylvie M. Asselin grad student 2005 Penn
Allyn T. Londregan grad student 2006 Penn
Emily C. McLaughlin grad student 2006 Penn
Justin R. Ragains grad student 2006 Penn
Thomas Haimowitz grad student 2007 Penn
Peter J. Mikochik grad student 2002-2007 Penn
Mohammad R. Imam grad student 2008 Penn
Esther C. Lee grad student 2008 Penn
Andre K. Isaacs grad student 2011 Penn
Sara R Goldstein grad student 2011-2017 Penn
Robert A. Batey post-doc Penn
Michael F. Greaney post-doc Penn
Michelle A. Sanchez post-doc
Qiao Yan post-doc 2017-2018 Penn
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Publications

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Cechakova L, Ondrej M, Pavlik V, et al. (2019) A Potent Autophagy Inhibitor (Lys05) Enhances the Impact of Ionizing Radiation on Human Lung Cancer Cells H1299. International Journal of Molecular Sciences. 20
Yan Q, Carroll PJ, Gau MR, et al. (2019) A Transannular Rearrangement Reaction of a Pyrroloindoline Diketopiperazine. Organic Letters
Wangtrakuldee P, Adeniji AO, Zang T, et al. (2019) A 3-(4-Nitronaphthen-1-yl) amino-benzoate analog as a Bifunctional AKR1C3 Inhibitor with AR Antagonist Activity: Head to Head Comparison with Other Advanced AKR1C3 Targeted Therapeutics. The Journal of Steroid Biochemistry and Molecular Biology
Rebecca VW, Nicastri MC, Fennelly C, et al. (2018) PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer. Cancer Discovery
Baquero P, Dawson A, Mukhopadhyay A, et al. (2018) Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia
Goldstein SR, Liu C, Safo MK, et al. (2018) Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. Acs Medicinal Chemistry Letters. 9: 714-718
Nicastri MC, Rebecca VW, Amaravadi RK, et al. (2018) Dimeric quinacrines as chemical tools to identify PPT1, a new regulator of autophagy in cancer cells. Molecular & Cellular Oncology. 5: e1395504
Nakamura E, Winkler JD, Aggarwal VK. (2017) Gilbert Stork (1921-2017). Angewandte Chemie (International Ed. in English)
Piao S, Ojha R, Rebecca VW, et al. (2017) ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells. Autophagy. 1-16
Rebecca VW, Nicastri MC, McLaughlin N, et al. (2017) A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery
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