Jeffery W. Kelly, Ph.D.

Affiliations: 
Chemistry and Molecular Medicine Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Chemical Biology, protein folding
Website:
http://www.scripps.edu/skaggs/kelly/dr_kelly.php?a=l&cid=1
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"Jeffery Kelly"
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Parents

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Slayton A. Evans grad student 1986 UNC Chapel Hill
 (I. The mechanism, stereochemistry, and scope of dioxyphosphorane promoted cyclodehydrations ; II. Oxygen-17 NMR studies directed towards elucidating the structure and dynamics of oxygenated organosulfur and organosilicon compounds)
Emil Thomas Kaiser post-doc 1989 Rockefeller

Children

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Douglas M. Fowler grad student Scripps Institute
Sarah J. Siegel grad student Scripps Institute
Derrick Suk Tong Ong grad student Scripps Institute
Rockland Luke Wiseman grad student Scripps Institute
Wilfredo Colon grad student 1989-1992 Texas A&M University, The Scripps Research Institute
Joel P. Schneider grad student 1995 Texas A & M
Hilal A. Lashuel grad student 1994-1999 Texas A & M
Hank Michael Petrassi grad student 2001 Scripps Institute
Hans Edward Purkey grad student 2002 Scripps Institute
Joleen Terese White grad student 2002 Scripps Institute
Mary Elizabeth Huff grad student 2003 Scripps Institute
Songpon Deechongkit grad student 2000-2004 Scripps Institute
Anupama R. Sawkar grad student 2005 Scripps Institute
R. Luke Wiseman grad student 2005 Scripps Institute
Steven M. Johnson grad student 2006 Scripps Institute
Lisa M. Ryno grad student 2012 Scripps Institute
Wentao Chen grad student 2010-2016 Scripps Institute
Maziar S. Ardejani post-doc Scripps Institute
Amy R. (Hurshman) Babbes post-doc
Paul W. Baures post-doc Scripps Institute
Lyudmila Bazhenova post-doc Scripps Institute
Jan Bieschke post-doc Scripps Institute
Sungwook Choi post-doc Scripps Institute
Nora Green post-doc Scripps Institute
Per Hammarstrom post-doc Scripps Institute
John D. Hulleman post-doc Scripps Institute
Jiyong Lee post-doc Scripps Institute
Fernando L. Palhano post-doc Scripps Institute
Jose M. Rivera post-doc Scripps Institute
Yoshiki Sekijima post-doc Scripps Institute
Xin Zhang post-doc Scripps Institute
Qinghai Zhang post-doc Scripps Institute
Evan T. Powers post-doc 1997-2000 Scripps Institute
Shu-li You post-doc 2001-2004 Scripps Institute
Shuli You post-doc 2001-2004 The Scripps Research Institute, California, USA
Daryl A. Bosco post-doc 2003-2005 Scripps Institute
Jianmin Gao post-doc 2004-2007 Scripps Institute
Laura Segatori post-doc 2005-2007 Scripps Institute
Paveen Nekkar post-doc 2005-2008 Scripps Institute
Amelia A. Fuller post-doc 2006-2009 Scripps Institute
Kenji Usui post-doc 2007-2009 Scripps Institute
Tingwei Mu post-doc 2005-2010 Scripps Institute
Deguo Du post-doc 2008-2010 Scripps Institute
Joshua L. Price post-doc 2008-2011 Scripps Institute
Joshua L. Price post-doc 2008-2011 Scripps Institute
Steven Bourgault post-doc 2009-2011 Scripps Institute
Matthew D. Shoulders post-doc 2009-2012 Scripps Institute
Christina Cooley post-doc 2011-2015 Scripps Institute
Lars Plate post-doc 2013-2017
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Publications

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Brighty GJ, Botham RC, Li S, et al. (2020) Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery. Nature Chemistry
Nelson LT, Paxman RJ, Xu J, et al. (2020) Blinded potency comparison of transthyretin kinetic stabilisers by subunit exchange in human plasma. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-6
Grandjean JMD, Madhavan A, Cech L, et al. (2020) Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nature Chemical Biology
Yan NL, Santos-Martins D, Rennella E, et al. (2020) Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins. Bioorganic & Medicinal Chemistry Letters. 30: 127356
Dasari AKR, Arreola J, Michael B, et al. (2020) Disruption of the CD loop by Enzymatic Cleavage Promotes the Formation of Toxic Transthyretin Oligomers through a Common Transthyretin Misfolding Pathway. Biochemistry
Dasari AKR, Hung I, Michael B, et al. (2020) Structural Characterization of Cardiac ex vivo Transthyretin Amyloid: Insight into Transthyretin Misfolding Pathway in vivo. Biochemistry
Dukovski D, Villella A, Bastos C, et al. (2020) Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Rennella E, Morgan GJ, Yan N, et al. (2019) The role of protein thermodynamics and primary structure in fibrillogenesis of variable domains from immunoglobulin light-chains. Journal of the American Chemical Society
Monteiro C, Mesgazardeh JS, Anselmo J, et al. (2019) Predictive model of response to tafamidis in hereditary ATTR polyneuropathy. Jci Insight. 4
Ruberg FL, Grogan M, Hanna M, et al. (2019) Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 73: 2872-2891
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