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Manu Kohli, Ph.D.

Affiliations: 
2000 Georgetown University Medical Center, Washington, DC, United States 
Area:
Biochemistry, Molecular Biology, Oncology
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Parents

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Timothy J. Jorgensen grad student 2000 Georgetown University Medical Center
 (Signaling, processing, and repair of ionizing radiation-induced DNA single- and double -strand breaks.)

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Publications

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Dang DT, Chen F, Kohli M, et al. (2005) Glutathione S-transferase pi1 promotes tumorigenicity in HCT116 human colon cancer cells. Cancer Research. 65: 9485-94
Cummins JM, Kohli M, Rago C, et al. (2004) X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Research. 64: 3006-8
Cummins JM, Rago C, Kohli M, et al. (2004) Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature. 428: 1 p following 486
Kohli M, Rago C, Lengauer C, et al. (2004) Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses Nucleic Acids Research. 32: e3
Kohli M, Jorgensen TJ. (1999) Lack of dependence on p53 for DNA double strand break repair of episomal vectors in human lymphoblasts. Biochemical and Biophysical Research Communications. 264: 702-8
Winters TA, Russell PS, Kohli M, et al. (1999) Determination of human DNA polymerase utilization for the repair of a model ionizing radiation-induced DNA strand break lesion in a defined vector substrate. Nucleic Acids Research. 27: 2423-33
Kohli M, Jorgensen TJ. (1999) The influence of SV40 immortalization of human fibroblasts on p53-dependent radiation responses. Biochemical and Biophysical Research Communications. 257: 168-76
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