Sama Tamrakar, Ph.D.

Affiliations: 
2000 University of Rochester, Rochester, NY 
Area:
Biochemistry, Cell Biology, Molecular Biology
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"Sama Tamrakar"
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John W. Ludlow grad student 2000 Rochester
 (Characterization of the interaction between the retinoblastoma protein and protein phosphatase type 1.)
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Publications

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Tamrakar S, Kapasi AJ, Spector DH. (2005) Human cytomegalovirus infection induces specific hyperphosphorylation of the carboxyl-terminal domain of the large subunit of RNA polymerase II that is associated with changes in the abundance, activity, and localization of cdk9 and cdk7. Journal of Virology. 79: 15477-93
Sanchez V, McElroy AK, Yen J, et al. (2004) Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production. Journal of Virology. 78: 11219-32
Krucher NA, Zygmunt A, Mazloum N, et al. (2000) Interaction of the retinoblastoma protein (pRb) with the catalytic subunit of DNA polymerase delta (p125). Oncogene. 19: 5464-70
Tamrakar S, Ludlow JW. (2000) The carboxyl-terminal region of the retinoblastoma protein binds non-competitively to protein phosphatase type 1alpha and inhibits catalytic activity. The Journal of Biological Chemistry. 275: 27784-9
Tamrakar S, Rubin E, Ludlow JW. (2000) Role of pRB dephosphorylation in cell cycle regulation. Frontiers in Bioscience : a Journal and Virtual Library. 5: D121-37
Tamrakar S, Mittnacht S, Ludlow JW. (1999) Binding of select forms of pRB to protein phosphatase type 1 independent of catalytic activity. Oncogene. 18: 7803-9
Rubin E, Tamrakar S, Ludlow JW. (1998) Protein phosphatase type 1, the product of the retinoblastoma susceptibility gene, and cell cycle control. Frontiers in Bioscience : a Journal and Virtual Library. 3: D1209-19
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