Natalie Strynadka

Affiliations: 
Biochemistry and Molecular Biology University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
structure-based design of novel, therapeutically useful antibiotics and inhibitors of antibiotic-resistance mechanisms
Website:
http://www.biochem.ubc.ca/faculty/natalie-strynadka/
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"Natalie Strynadka"
Bio:

http://www.hhmi.org/research/sirs/strynadka_bio.html

Mean distance: (not calculated yet)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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Michael N.G. James grad student 1990 University of Alberta
 (Probing molecular interactions at various levels of structural definition)

Children

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Nathanael A Caveney grad student
Calvin Yip grad student UBC
Trevor F. Moraes post-doc UBC
BETA: Related publications

Publications

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Lyons BJE, Atkinson CE, Deng W, et al. (2021) Cryo-EM structure of the EspA filament from enteropathogenic Escherichia coli: revealing the mechanism of effector translocation in the T3SS. Structure (London, England : 1993)
Bergeron JRC, Brockerman JA, Vuckovic M, et al. (2018) Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. Protein Science : a Publication of the Protein Society
Deng W, Marshall NC, Rowland JL, et al. (2017) Corrigendum: Assembly, structure, function and regulation of type III secretion systems. Nature Reviews. Microbiology. 15: 379
Deng W, Marshall NC, Rowland JL, et al. (2017) Assembly, structure, function and regulation of type III secretion systems. Nature Reviews. Microbiology
King AM, King DT, French S, et al. (2016) Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. Acs Chemical Biology
Bergeron JR, Fernández L, Wasney GA, et al. (2015) The Structure of a T3SS Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. The Journal of Biological Chemistry
Burkinshaw BJ, Souza SA, Strynadka NC. (2015) Structural analysis of SepL, an enteropathogenic Escherichia coli type III secretion-system gatekeeper protein. Acta Crystallographica. Section F, Structural Biology Communications. 71: 1300-8
Farha MA, Czarny TL, Myers CL, et al. (2015) Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase. Proceedings of the National Academy of Sciences of the United States of America. 112: 11048-53
Ghavami A, Labbé G, Brem J, et al. (2015) Assay for drug discovery: Synthesis and testing of nitrocefin analogues for use as β-lactamase substrates. Analytical Biochemistry
Baier F, Chen J, Solomonson M, et al. (2015) Distinct Metal Isoforms Underlie Promiscuous Activity Profiles of Metalloenzymes. Acs Chemical Biology. 10: 1684-93
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