Jean Anne Chmielewski

Affiliations: 
Purdue University, West Lafayette, IN, United States 
Area:
Chemical Biology
Website:
https://www.chem.purdue.edu/activity/public/profile/chem/jchmiele
Google:
"Jean A. Chmielewski"
Bio:

https://www.chem.purdue.edu/chml/
https://www.chem.purdue.edu/chml/chmielewski.php

Mean distance: 6.52
 
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Parents

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Ronald Charles David Breslow grad student 1988 Columbia
 (Transaminase and racemase activity of pyridoxal/pryidoxamine enzyme analogs)
Emil Thomas Kaiser post-doc 1988 Rockefeller
Peter G. Schultz post-doc 1990 UC Berkeley

Children

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Eric M. Brustad research assistant 2002 Purdue
Milata Abraham grad student Purdue
Neha Agrawal grad student Purdue
Patricia Bishop grad student Purdue
Reena Blade grad student Purdue
Anna Brezden grad student Purdue
Michelle Brickner grad student Purdue
Jeremy Gleaton grad student Purdue
Ray Lutgring grad student Purdue
Monessha Nambiar grad student Purdue
Manish Nepal grad student Purdue
Jennifer Rowe grad student Purdue
Michael Shultz grad student Purdue
Kevin Strauss grad student Purdue
Luckner Ulysse grad student Purdue
Karen Vogel-Pinette grad student Purdue
Reena Zutshi grad student Purdue
Indraneel Ghosh grad student 1998 Purdue
Shao Qin Yao grad student 1998 Purdue
Cynthia L. Micklatcher grad student 2000 Purdue
Young-Wan Ham grad student 2002 Purdue
Roy P. Issac grad student 2002 Purdue
Angela D. Ragin grad student 2003 Purdue
Hsien-Ming Lee grad student 2004 Purdue
You S. Hwang grad student 2005 Purdue
Lei Zhao grad student 2005 Purdue
Yannick Fillon grad student 2007 Purdue
Song-Gil Lee grad student 2007 Purdue
Brandon D. Gaddis grad student 2008 Purdue
Stefan J. Hershberger grad student 2008 Purdue
Iris M. Geisler grad student 2009 Purdue
David E. Przybyla grad student 2010 Purdue
Dawn M. Ernenwein grad student 2011 Purdue
Hilda A. Namanja grad student 2012 Purdue
Charles M. Rubert Perez grad student 2012 Purdue
Victor Hernandez Gordillo grad student 2013 Purdue
Jerrin Kuriakose grad student 2014 Purdue
Indraneel Ghosh post-doc Purdue
Marcos Pires post-doc 2009- Purdue
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Publications

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Nepal M, Mohamed M, Blade R, et al. (2018) A Library Approach to Cationic Amphiphilic Polyproline Helices that Target Intracellular Pathogenic Bacteria. Acs Infectious Diseases
Mohamed MF, Brezden A, Mohammad H, et al. (2017) A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Scientific Reports. 7: 6953
Namanja-Magliano HA, Bohn K, Agrawal N, et al. (2017) Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine. Bioorganic & Medicinal Chemistry
Bohn K, Lange A, Chmielewski J, et al. (2017) Dual Modulation of Human P-glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood-Brain Barrier. Molecular Pharmaceutics
Mohamed MF, Brezden A, Mohammad H, et al. (2017) Targeting biofilms and persisters of ESKAPE pathogens with P14KanS, a kanamycin peptide conjugate. Biochimica Et Biophysica Acta. 1861: 848-859
Strauss K, Chmielewski J. (2017) Advances in the design and higher-order assembly of collagen mimetic peptides for regenerative medicine. Current Opinion in Biotechnology. 46: 34-41
Strauss K, Chmielewski J. (2016) Metal-Promoted Assembly of Two Collagen Mimetic Peptides into a Biofunctional "Spiraled Horn" Scaffold. Materials (Basel, Switzerland). 9
Nepal M, Sheedlo MJ, Das C, et al. (2016) Accessing Three-Dimensional Crystals with Incorporated Guests through Metal-Directed Coiled-Coil Peptide Assembly. Journal of the American Chemical Society
Brezden A, Mohamed MF, Nepal M, et al. (2016) Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial, Cell Penetrating Peptide. Journal of the American Chemical Society
Thangamani S, Nepal M, Chmielewski J, et al. (2015) Antibacterial activity and therapeutic efficacy of Fl-P(R)P(R)P(L)-5, a cationic amphiphilic polyproline helix, in a mouse model of staphylococcal skin infection. Drug Design, Development and Therapy. 9: 5749-54
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