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James L. Leighton

Affiliations: 
Columbia University, New York, NY 
Area:
Organic synthesis
Website:
http://www.columbia.edu/cu/chemistry/groups/leighton/leighton.html
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"James Leighton"
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Parents

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Samuel J. Danishefsky research assistant 1987 Yale
David A. Evans grad student 1994 Harvard
Eric N. Jacobsen post-doc 1996 Harvard

Children

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Noah Z. Burns research assistant Columbia
Won Seok Ham research assistant 2012-2013 Columbia
Matthew M. Bio grad student 2001 Columbia
Stella T. Sarraf grad student 2001 Columbia
Keith R. Hornberger grad student 2002 Columbia
Christine M. DiBlasi grad student 2003 Columbia
Isaac J. Krauss grad student 2003 Columbia
Pui Y. Ng grad student 2003 Columbia
Michael J. Zacuto grad student 2003 Columbia
Richard Berger grad student 2004 Columbia
Bastien Castagner grad student 2004 Columbia
Christopher L. Hamblett grad student 2004 Columbia
Steven J. O'Malley grad student 2004 Columbia
Sergey Bolshakov grad student 2005 Columbia
Xiaolun Wang grad student 2005 Columbia
Blaine M. Hackman grad student 2006 Columbia
Pamela J. Lombardi grad student 2006 Columbia
Philippe M. Rabbat grad student 2006 Columbia
Arash Soheili grad student 2004-2008 Columbia
Kristy Tran grad student 2009 Columbia
Jenny M. Baxter grad student 2010 Columbia
Miriam I. Feske grad student 2010 Columbia
S. C. Valdez grad student 2010 Columbia
Sharon K. Lee grad student 2012 Columbia
Christopher W. Plummer grad student 2012 Columbia
Samuel K. Reznik grad student 2012 Columbia
Alexander Buitrago Santanilla grad student 2013 Columbia
Corinne N. Foley grad student 2015 Columbia
Uttam Krishan Tambar post-doc UT Southwestern
Seiji Shirakawa post-doc 2004-2005 Columbia

Collaborators

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Publications

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Suen LM, Tekle-Smith MA, Williamson KS, et al. (2018) Design and 22-step synthesis of highly potent D-ring modified and linker-equipped analogs of spongistatin 1. Nature Communications. 9: 4710
Tekle-Smith MA, Williamson KS, Hughes IF, et al. (2017) Direct, Mild, and General n-Bu4NBr-Catalyzed Aldehyde Allylsilylation with Allyl Chlorides. Organic Letters
Foley CN, Chen LA, Sackett DL, et al. (2017) Synthesis and Evaluation of a Linkable Functional Group-Equipped Analogue of the Epothilones. Acs Medicinal Chemistry Letters. 8: 701-704
Su TA, Li H, Klausen RS, et al. (2017) Silane and Germane Molecular Electronics. Accounts of Chemical Research
Chen LA, Ashley MA, Leighton JL. (2017) Evolution of an Efficient and Scalable Nine-Step (LLS) Synthesis of Zincophorin Methyl Ester. Journal of the American Chemical Society
Foley CN, Leighton JL. (2015) A Highly Stereoselective, Efficient, and Scalable Synthesis of the C(1)-C(9) Fragment of the Epothilones. Organic Letters
Ho S, Sackett DL, Leighton JL. (2015) A "Methyl Extension" Strategy for Polyketide Natural Product Linker Site Validation and Its Application to Dictyostatin. Journal of the American Chemical Society. 137: 14047-50
Plummer CW, Wei CS, Yozwiak CE, et al. (2015) Correction to "Design, Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core". Journal of the American Chemical Society. 137: 13722
Plummer CW, Wei CS, Yozwiak CE, et al. (2014) Design, development, mechanistic elucidation, and rational optimization of a tandem Ireland Claisen/Cope rearrangement reaction for rapid access to the (iso)cyclocitrinol core. Journal of the American Chemical Society. 136: 9878-81
Foley CN, Leighton JL. (2014) Beyond the roche ester: A new approach to polypropionate stereotriad synthesis Organic Letters. 16: 1180-1183
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