Richard B. Silverman

Affiliations:

1976-

Northwestern University, Evanston, IL

Area:

Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology

Website:

https://silverman.northwestern.edu/research/

Google:

"Richard Silverman"

Bio:

(born 1946)

Mean distance: 8.01

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Parents

David H. Dolphin	grad student	1971-1974	Harvard
(Model Studies for Coenzyme B12-Dependent Enzyme-Catalyzed Rearrangements.)
Robert Heinz Abeles	post-doc	1974-1976	Brandeis

Children

Walter Fast	grad student
John S. Oliver	grad student	1988	Northwestern
Boyu Zhong	grad student	1998	Northwestern
Hui Huang	grad student	2000	Northwestern
Deanna J. Mitchell	grad student	2000	Northwestern
Jung-Mi Hah	grad student	2002	Northwestern
Christine A. Schering	grad student	2004	Northwestern
Elizabeth A. Litzinger	grad student	2005	Northwestern
Zhiyong Wang	grad student	2005	Northwestern
Erik P. Erdal	grad student	2006	Northwestern
Jiwon Seo	grad student	2006	Northwestern
Hai Yuan	grad student	2006	Northwestern
Yaoqiu Zhu	grad student	2006	Northwestern
Graham R. Lawton	grad student	2007	Northwestern
Lada Klaic	grad student	2010	Northwestern
Tian Chen	grad student	2011	Northwestern
Kristin J. Labby	grad student	2012	Northwestern
Dustin D. Hawker	grad student	2013	Northwestern
Robert P. Dixon	post-doc		Northwestern
Isaac T Schiefer	post-doc
Paul Trippier	post-doc		Northwestern (Neurotree)
Soosung Kang	post-doc	2009-2013	Science
Jose I. Juncosa	post-doc	2011-2014	Northwestern
Hoang V. Le	post-doc	2016	Northwestern
Pathum Weerawarna	post-doc	2016-2021	Northwestern

Collaborators

Dali Liu

collaborator

BETA: Related publications

Publications

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Lykins J, Moschitto MJ, Zhou Y, et al. (2023) From O/GABA-AT, GABA, and T-263 Mutant to Conception of . Iscience. 27: 108477
Vasu D, Li H, Hardy CD, et al. (2022) 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors. Bioorganic & Medicinal Chemistry. 69: 116878
Yun J, Jeong D, Xie Z, et al. (2022) Palladium-Catalyzed α-Arylation of Cyclic β-Dicarbonyl Compounds for the Synthesis of Ca1.3 Inhibitors. Acs Omega. 7: 14252-14263
Zhu W, Butrin A, Melani RD, et al. (2022) Rational Design, Synthesis, and Mechanism of (3,4)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase. Journal of the American Chemical Society
Cooper G, Kang S, Perez-Rosello T, et al. (2021) Correction to A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca1.3 L-Type Calcium Channels. Acs Chemical Biology
Zhu W, Doubleday PF, Butrin A, et al. (2021) Remarkable and Unexpected Mechanism for ()-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase. Journal of the American Chemical Society
Weerawarna PM, Moschitto MJ, Silverman RB. (2021) Theoretical and Mechanistic Validation of Global Kinetic Parameters of the Inactivation of GABA Aminotransferase by OV329 and CPP-115. Acs Chemical Biology
Shen S, Doubleday PF, Weerawarna PM, et al. (2020) Mechanism-Based Design of 3-Amino-4-Halocyclopentenecarboxylic Acids as Inactivators of GABA Aminotransferase. Acs Medicinal Chemistry Letters. 11: 1949-1955
Cooper G, Kang S, Perez-Rosello T, et al. (2020) A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca1.3 L-Type Calcium Channels. Acs Chemical Biology
Catlin DS, Reidl CT, Trzupek TR, et al. (2020) (S)-4-Amino-5-phenoxypentanoate Designed as a Potential Selective Agonist of the Bacterial Transcription Factor GabR. Protein Science : a Publication of the Protein Society