Franklin Arnold Davis

Temple University, Philadelphia, PA, United States 
Asymmetric Synthesis
"Franklin Davis"
Franklin Davis received his BS degree in chemistry from the University of Wisconsin and a Ph.D. from Syracuse University (1966) with Donald Dittmer, exploring thiete (thiacyclobutene) chemistry. Following postdoctoral work with Michael J. S. Dewar at the University of Texas developing organoboron chemistry, he joined the faculty at Drexel University in 1968, initiating studies in organosulfur chemistry and asymmetric reagent development. In 1986 he was named the George S. Sasin Professor of Organic Chemistry. In 1995 he moved across town to Temple University.

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Donald C. Dittmer grad student 1966 Syracuse
 (The synthesis and reactions of derivatives of thiacyclobutene)
Michael J. S. Dewar post-doc 1968 UT Austin
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Davis FA. (2016) Heterocyclic synthesis using the intramolecular Mannich cyclization reaction and enantiopure N-sulfinyl β-amino carbonyl compounds Phosphorus, Sulfur and Silicon and the Related Elements. 191: 297-304
Hung SW, Mody H, Marrache S, et al. (2013) Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies. Plos One. 8: e71196
Reith ME, Ali S, Hashim A, et al. (2012) Novel C-1 substituted cocaine analogs unlike cocaine or benztropine. The Journal of Pharmacology and Experimental Therapeutics. 343: 413-25
Edupuganti R, Davis FA. (2012) Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis. Organic & Biomolecular Chemistry. 10: 5021-31
Davis FA, Gaddiraju NV, Theddu N, et al. (2012) Enantioselective synthesis of cocaine C-1 analogues using sulfinimines (N-sulfinyl imines). The Journal of Organic Chemistry. 77: 2345-59
Davis FA, Xu H. (2012) Formal synthesis of (-)-Clavepictine A and (+)- Clavepictine B from A sulfinimine (N-sulfinylimine)- Derived chiral building block Heterocycles. 84: 1227-1233
Davis FA, Xu P. (2011) Asymmetric synthesis of anti-α-substituted β-amino ketones from sulfinimines. The Journal of Organic Chemistry. 76: 3329-37
Davis FA, Zhang J, Wu Y. (2011) Total syntheses of (+)-monomorine I and (-)-indolizidine 195B from sulfinimine-derived 3-oxo pyrrolidine 2-phosphonates Tetrahedron Letters. 52: 2054-2057
Davis FA, Theddu N, Edupuganti R. (2010) Asymmetric total synthesis of (S)-(+)-cocaine and the first synthesis of cocaine C-1 analogs from N-sulfinyl β-amino ester ketals. Organic Letters. 12: 4118-21
Davis FA, Theddu N. (2010) Asymmetric synthesis of cyclic cis-beta-amino acid derivatives using sulfinimines and prochiral Weinreb amide enolates. The Journal of Organic Chemistry. 75: 3814-20
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