John A. Porco, Jr.

Affiliations: 
Boston University, Boston, MA, United States 
Area:
synthesis of complex natural products
Website:
http://www.bu.edu/chemistry/faculty/porco/
Google:
"John A. Porco, Jr."
Bio:

http://cmld.bu.edu/center/personnel/

Mean distance: 6.89
 
SNBCP

Parents

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Stuart L. Schreiber grad student 1992 Harvard
 (Studies toward the synthesis of the enediyne antibiotics)
Chi-Huey Wong post-doc Scripps Institute

Children

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Adam Zahara research assistant 2018
Wenyu Wang grad student
Yuan Xiong grad student
Qiang Zhang grad student Boston University
Chaomin Li grad student 2005 Boston University
Ruichao Shen grad student 2005 Boston University
Xiang Wang grad student 1999-2005 Boston University
Sujata Bardhan grad student 2007 Boston University
Xiaoguang Lei grad student 2007 Boston University
Shun Su grad student 2007 Boston University
Jianglong Zhu grad student 2007 Boston University
Baudouin Gerard grad student 2008 Boston University
Chong Han grad student 2008 Boston University
Andrew Germain grad student 2010 Boston University
Ji Qi grad student 2010 Boston University
Suwei Dong grad student 2011 Boston University
Andrew S. Kleinke grad student 2011 Boston University
David L. Sloman grad student 2011 Boston University
Stephen S. Scully grad student 2012 Boston University
Andrew J. Little grad student 2013 Boston University
Anais Gervais grad student 2014 Boston University
Neil J. Lajkiewicz grad student 2015 Boston University
Jonathan H Boyce grad student 2011-2017 Boston University
Branko Mitasev post-doc Boston University
Stéphane P. Roche post-doc 2008-2011 Boston University
Spandan Chennamadhavuni post-doc 2012-2014
Alex J. Grenning post-doc 2012-2014 Boston University
Lauren E. Brown research scientist 2012-2014 Boston University
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Publications

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Yang F, Porco JA. (2022) Unified, Asymmetric Total Synthesis of the Asnovolins and Related Spiromeroterpenoids: A Fragment Coupling Approach. Journal of the American Chemical Society
Lehman SL, Wechsler T, Schwartz K, et al. (2022) Inhibition of the translation initiation factor eIF4A enhances tumor cell radiosensitivity. Molecular Cancer Therapeutics
Praditya DF, Klöhn M, Brüggemann Y, et al. (2022) Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication. Antiviral Research. 105359
Xu W, Brown LE, Porco JA. (2021) Divergent, C-C Bond Forming Macrocyclizations Using Modular Sulfonylhydrazone and Derived Substrates. The Journal of Organic Chemistry
Chatterjee S, Yabaji SM, Rukhlenko OS, et al. (2021) Channeling macrophage polarization by rocaglates increases macrophage resistance to . Iscience. 24: 102845
Iyer KR, Camara K, Daniel-Ivad M, et al. (2020) An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris. Nature Communications. 11: 6429
Levi-Galibov O, Lavon H, Wassermann-Dozorets R, et al. (2020) Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer. Nature Communications. 11: 6245
Boyce JH, Reisman BJ, Bachmann BO, et al. (2020) Synthesis and Multiplexed Activity Profiling of Synthetic Acylphloroglucinol Scaffolds. Angewandte Chemie (International Ed. in English)
Iyer KR, Whitesell L, Porco JA, et al. (2020) Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris. Mbio. 11
Chu J, Zhang W, Cencic R, et al. (2020) Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F. Cell Reports
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