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Arun K. Ghosh

Affiliations: 
Purdue University, West Lafayette, IN, United States 
Area:
HIV-1 protease inhibitors
Website:
http://www.chem.purdue.edu/ghosh/
Google:
"Arun Ghosh"
Bio:

http://media.iupac.org/news/archives/2010/IUPAC_Richter_Prize_2010.pdf

Mean distance: 7.29
 
SNBCP

Parents

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Alan P. Kozikowski grad student 1985 University of Pittsburgh
 (Stereoselection in nitrile oxide cycloaddition, metalation-alkylation of isoxazlines and their application to the synthesis of 2-deoxy-D-ribose, (+)-Blastmycinone, and (+)-Prelog-Djerassi lactone. Part II, Pyranoannulation and an enantioselective ...)
Elias James Corey post-doc 1985-1988 Harvard

Children

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Xiaoming Xu grad student 2008 Purdue
Sarang S. Kulkarni grad student 2009 Purdue
Kai Xi grad student 2009 Purdue
Sofiya Yashchuk grad student 2010 Purdue
Hao Yuan grad student 2011 Purdue
Zachary L. Dawson grad student 2012 Purdue
Jorden P. Kass grad student 2012 Purdue
Khriesto A. Shurrush grad student 2013 Purdue
Chad A. Keyes grad student 2014 Purdue
Prasanth Reddy Nyalapatla grad student 2012-2017 Purdue
Heather L Osswald grad student 2012-2017 Purdue
Perali Ramu Sridhar post-doc 2004-2006 Purdue
Gangarajula Sudhakar post-doc 2007-2008 Purdue
Koena Ghosh post-doc 2009-2011 Purdue
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Publications

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Ghosh AK, Raghavaiah J, Shahabi D, et al. (2021) Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. Journal of Medicinal Chemistry
Agniswamy J, Kneller DW, Ghosh AK, et al. (2021) Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PR. Biochemical and Biophysical Research Communications. 566: 30-35
Ghosh AK, Yadav M. (2021) Highly Diastereoselective Intramolecular Asymmetric Oxidopyrylium-olefin [5 + 2] Cycloaddition and Synthesis of 8-Oxabicyclo[3.2.1]oct-3-enone Containing Ring Systems. The Journal of Organic Chemistry
Ghosh AK, Mishevich JL, Jurica MS. (2021) Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors. Journal of Natural Products
Ghosh AK, Hsu CS. (2021) Enantioselective Total Synthesis of (+)-EBC-23, a Potent Anticancer Agent from the Australian Rainforest. The Journal of Organic Chemistry
Gamboa Lopez A, Allu SR, Mendez P, et al. (2021) Herboxidiene Features That Mediate Conformation-Dependent SF3B1 Interactions to Inhibit Splicing. Acs Chemical Biology
Yen YC, Kammeyer AM, Tirlangi J, et al. (2021) A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors. Acs Chemical Neuroscience
Hattori SI, Higashi-Kuwata N, Hayashi H, et al. (2021) A small moleculeĀ compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nature Communications. 12: 668
Ghosh AK, Allu SR, Reddy GC, et al. (2021) Design and synthesis of herboxidiene derivatives that potently inhibit splicing. Organic & Biomolecular Chemistry
Ghosh AK, Shahabi D. (2021) Synthesis of amide derivatives for electron deficient amines and functionalized carboxylic acids using EDC and DMAP and a catalytic amount of HOBt as the coupling reagents. Tetrahedron Letters. 63
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